JAMDA
Volume 5, Issue 1 , Pages 24-30 , January 2004

The Effect of Megestrol Acetate on Oral Food and Fluid Intake in Nursing Home Residents: A Pilot Study

  • Sandra F. Simmons, PhD

      Affiliations

    • University of California, Los Angeles, School of Medicine, Department of Geriatrics, Borun Center for Gerontological Research, Los Angeles, CA
    • Jewish Home for Aging Research, Reseda, CA
    • Corresponding Author InformationAddress correspondence to Sandra F. Simmons, PhD, Jewish Home for the Aging/UCLA Borun Center for Gerontological Research, 7150 Tampa Avenue, Reseda, CA 91335.
    • ,
  • Kathleen A. Walker

      Affiliations

    • University of California, Los Angeles, School of Medicine, Department of Geriatrics, Borun Center for Gerontological Research, Los Angeles, CA
    • Jewish Home for Aging Research, Reseda, CA
    • ,
  • Dan Osterweil, MD, CMD

      Affiliations

    • University of California, Los Angeles, School of Medicine, Department of Geriatrics, Borun Center for Gerontological Research, Los Angeles, CA

References 

  1. Pokrywka HS , Koffler KH , Remsburg R , et al.   Accuracy of patient care staff in estimating and documenting meal intake of nursing home residents . J Am Geriatr Soc . 1997;45:1223–1227
  2. Simmons SF , Lim B , Schnelle JF . Accuracy of minimum data set in identifying residents at risk for undernutrition: Oral intake and food complaints . J Am Med Dir Assoc . 2002;2:140–145
  3. Simmons SF , Osterweil D , Schnelle JF . Improving food and fluid intake in nursing home residents with feeding assistance: A staffing analysis . J Gerontol A Biol Sci Med Sci . 2001;56A:M790–M794
  4. Simmons SF , Reuben D . Nutritional intake monitoring for nursing home residents: A comparison of staff documentation, direct observation, and photography methods . J Am Geriatr Soc . 2000;48:209–213
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  7. Blaum CS , Fries BE , Fiatarone MA . Factors associated with low body mass index and weight loss in nursing home residents . J Gerontol A Biol Sci Med Sci . 1995;50A:M162–M168
  8. Ferguson RP , O'Conner P , Crabtree B , et al.   Serum albumin and prealbumin as predictors of clinical outcomes of hospitalized elderly nursing home residents . J Am Geriatr Soc . 1993;41:545–549
  9. Morley JE , Silver AJ . Nutritional issues in nursing home care . Ann Intern Med . 1995;123:850–859
  10. Kayser-Jones J , Schell E . The effect of staffing on the quality of care at mealtime . Nurs Outlook . 1997;45:64–72
  11. Lange-Alberts ME , Shott S . Nutritional intake: Use of touch and verbal cuing . J Gerontol Nurs . 1994;2:36–40
  12. Manning AM , Means JG . A self-feeding program for geriatric patients in a skilled nursing facility . J Am Diet Assoc . 1975;66:275–276
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  14. Osborn CL , Marshall M . Promoting mealtime independence . Geriatr Nurs . 1992;13:254–256
  15. Van Ort S , Phillips LR . Nursing interventions to promote functional feeding . J Gerontol Nurs . 1995;10:6–14
  16. Jatoi A , Windschitl HE , Loprinzi CL , et al.   Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: A North Central Cancer Treatment Group study . J Clin Oncol . 2002;20:567–573
  17. Weisberg J , Wanger J , Olson J , et al.   Megestrol acetate stimulates weight gain and ventilation in underweight COPD patients . Chest . 2002;121:1070–1078
  18. Rosen GH . Pharmacologic agents used for nutritional disorders of HIV/AIDS . J Int Assoc Physicians AIDS Care . 1995;2:30–32
  19. Yeh S , Wu S , Levine DM , et al.   The correlation of cytokine levels with body weight after megestrol acetate treatment in geriatric patients . J Gerontol A Biol Sci Med Sci . 2001;56A:M48–M54
  20. Castle S , Nguyen C , Joaquin A , et al.   Megestrol acetate suspension therapy in the treatment of geriatric anorexia/cachexia in nursing home patients . J Am Geriatr Soc . 1995;43:835–836
  21. Raney MS , Anding R , Fay V , et al.   A pilot study to assess the use of megestrol acetate to promote weight gain in frail elderly persons residing in long-term care . J Am Med Dir Assoc . 2000;1:154–158
  22. Yeh S , Wu S , Lee T , et al.   Improvement in quality-of-life measures and stimulation of weight gain after treatment with megestrol acetate oral suspension in geriatric cachexia: Results of a double-blind, placebo controlled study . J Am Geriatr Soc . 2000;48:485–492
  23. Molloy DW , Alemayehu E , Roberts RA . Standardized Mini-Mental State Examination (SMMSE): Its reliability compared to the traditional Mini-Mental State Examination (MMSE) . Am J Psychiatry . 1991;148:102–105
  24. Megace Oral Suspension: Patient Guide to Therapy . Princeton, NJ: Bristol-Myers Squibb Co; 1997;
  25. Gilmore SA , Robinson G , Posthauer ME , et al.   Clinical indicators associated with unintentional weight loss and pressure ulcers in elderly residents in nursing facilities . J Am Diet Assoc . 1995;95:984–992
  26. Simmons SF, Schnelle JF. Individualized feeding assistance care for nursing home residents: Staffing requirements to implement two interventions. J Gerontol A Biol Sci Med Sci (in press).
  27. Kayser-Jones J , Schell ES , Porter C , et al.   A prospective study of the use of liquid oral dietary supplements in nursing homes . J Am Geriatr Soc . 1998;46:1378–1386
  28. Simmons SF , Lam H , Rao G , et al.   Family members' preferences for improving nursing home residents' oral food and fluid intake . J Am Geriatr Soc . 2003;51:1–6

PII: S1525-8610(04)70040-7

JAMDA
Volume 5, Issue 1 , Pages 24-30 , January 2004

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