JAMDA
Volume 7, Issue 9 , Pages 556-561 , November 2006

Efficacy of an Herbal Dietary Supplement (Smooth Move) in the Management of Constipation in Nursing Home Residents: A Randomized, Double-Blind, Placebo-Controlled Study

  • Sam Bub, MD

      Affiliations

    • Cedarbrook Nursing Home, Allentown, PA
    • Corresponding Author InformationAddress correspondence to Sam Bub, MD, 619 Dalton Street, Emmaus, PA 18049.
  • ,
  • Josef Brinckmann

      Affiliations

    • Traditional Medicinals, Inc., Sebastopol, CA
  • ,
  • Greg Cicconetti, PhD

      Affiliations

    • Muhlenberg College, Allentown, PA.
  • ,
  • Barbara Valentine, RN

      Affiliations

    • Cedarbrook Nursing Home, Allentown, PA

References 

  1. NHS Centre for Reviews and Dissemination. The management of constipation. Prescribing Nurse Bulletin. 1999;1(6):21–25
  2. Petticrew M, Watt I, Sheldon T. Systematic review of the effectiveness of laxatives in the elderly. Health Technol Assess. 1997;1(13):1–52i–iv
  3. Gossel TA. Management of constipation in institutionalized, immobilized, and elderly patients. New York, NY: Power-Pak C.E., Inc. Jobson Publishing; 2002;June 1. Pharmacy Program No. 424-000-02-004-H01
  4. Thomas DR, Forrester L, Gloth MF, et al. Clinical consensus: The constipation crisis in long-term care. Ann Long-Term Care. 2003;11(Suppl):3–14
  5. Volicer L, Lane P, Panke J, Lyman P. Management of constipation in residents with dementia: Sorbitol effectiveness and cost. J Am Med Dir Assoc. 2004;5(4):239–241
  6. Frank L, Schmier J, Kleinman L, et al. Time and economic cost of constipation care in nursing homes. J Am Med Dir Assoc. 2002;3:215–223
  7. Wald A. Is chronic use of stimulant laxatives harmful to the colon?. J Clin Gastroenterol. 2003;36(5):386–389
  8. In:  Braun R,  Surmann P,  Wendt R,  Wichtl M,  Ziegenmeyer J editor. Standardzulassungen für Fertigarzneimittel: Text und Kommentar, 13 (Ergänzungslieferung). Stuttgart, Germany: Deutscher Apotheker Verlag; 2000;Sennesblätter. Zulassungsnummer 7399.99.99
  9. World Health Organization (WHO). Radix glycyrrhizae monograph. In: WHO Monographs on Selected Medicinal Plants. Volume 1:Geneva, Switzerland: World Health Organization; 1999;p. 183–194
  10. In:  Wichtl M editors. Herbal Drugs and Phytopharmaceuticals—A Handbook for Practice on a Scientific Basis. English 3rd edition. Stuttgart, Germany: Medpharm Scientific Publishers; 2004;Brinckmann J, Lindenmaier M, translators
  11. Agra Y, Sacristán A, González M, et al. Efficacy of senna versus lactulose in terminal cancer patients treated with opioids. J Pain Symptom Manage. 1998;15(1):1–7
  12. Kinnunen O, Winblad I, Koistinen P, Salokannel J. Safety and efficacy of a bulk laxative containing senna versus lactulose in the treatment of chronic constipation in geriatric patients. Pharmacology. 1993;47(Suppl 1):253–255
  13. MacLennan WJ, Pooler AFWM. A comparison of sodium picosulphate (Laxoberal) with standardized senna (Senokot) in geriatric patients. Curr Med Res Opin 1974–75;2(10):641-647.
  14. Maddi VI. Regulation of bowel function by a laxative/stool softener preparation in aged nursing home patients. J Am Geriatr Soc. 1979;27(10):464–468
  15. Passmore AP, Davies KW, Flanagan PG, Stoker C, Scott MG. A comparison of Agiolax and lactulose in elderly patients with chronic constipation. Pharmacology. 1993;47(Suppl 1):249–252
  16. Pers M, Pers B. A crossover comparative study with two bulk laxatives. J Int Med Res. 1983;11(1):51–53
  17. Ramesh PR, Kumar KS, Rajagopal MR, et al. Managing morphine-induced constipation—A controlled comparison of an Ayurvedic formulation and senna. J Pain Symptom Manage. 1998;16(4):240–244
  18. Sharma BG. Safety and efficacy of Ayulax herbal supplement LAX (Ayurvedic capsules) in patients suffering from constipation [unpublished manuscript]. Mumbai, India: Maruti Clinic; 2000;

PII: S1525-8610(06)00334-3

doi: 10.1016/j.jamda.2006.06.001

JAMDA
Volume 7, Issue 9 , Pages 556-561 , November 2006