JAMDA
Volume 10, Issue 5 , Pages 289-291 , June 2009

Polypharmacy in the Nursing Home

  • John E. Morley, MB, BCh

      Affiliations

    • Corresponding Author InformationAddress correspondence to John E. Morley, MB, BCh, Division of Geriatric Medicine, Saint Louis University School of Medicine, 1402 S. Grand Boulevard, M238, St. Louis, MO 63104.

References 

  1. Abelland van Kan G, Rolland YM, Morley JE, Vellas B. Frailty: Toward a clinical definition. J Am Med Dir Assoc. 2008;9:71–72
  2. Abellan van Kan G, Rolland Y, Bergman H, et al. The IANA Task Force on frailty assessment of older people in clinical practice. J Nutr Health Aging. 2008;12:29–37
  3. Morley JE, Perry HM, Miller DK. Editorial: Something about frailty. J Gerontol A Biol Sci Med Sci. 2002;57:M698–M704
  4. Rockwood K, Abeysundera MJ, Mitnitski A. How should we grade frailty in nursing home patients?. J Am Med Dir Assoc. 2007;8:595–603
  5. Fick DM, Cooper JW, Wade WE, et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: Results of a US consensus panel of experts. Arch Intern Med. 2003;163:2716–2724
  6. Morley JE. Phronesis and the medical director. J Am Med Dir Assoc. 2009;10:149–152
  7. Reimersma-van der Lek RF, Swaab DF, Twisk J, et al. Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: A randomized controlled trial. JAMA. 2008;299:2642–2655
  8. De Lepeleire J, Bouwen A, De Coninck L, Buntinx F. Insufficient lighting in nursing homes. J Am Med Dir Assoc. 2007;8:314–317
  9. Fox T, Jacobs M. The magic of exercise. J Am Med Dir Assoc. 2008;9:375–377
  10. Colberg SR, Somma CT, Sechrist SR. Physical activity participation may offset some of the negative effects of diabetes on cognitive function. J Am Med Dir Assoc. 2008;9:434–438
  11. Rolland Y, Abellan van Kan G, Vellas B. Physical activity and Alzheimer's disease: From prevention to therapeutic perspectives. J Am Med Dir Assoc. 2008;9:390–405
  12. Morley JE. The magic of exercise. J Am Med Dir Assoc. 2008;9:375–377
  13. Morley JE. Managing persons with dementia in the nursing home: High touch trumps high tech. J Am Med Dir Assoc. 2008;9:139–146
  14. Hui EK, Rubenstein LZ. Promoting physical activity and exercise in older adults. J Am Med Dir Assoc. 2006;7:310–314
  15. Raina P, Santaguida P, Ismaila A, et al. Effectiveness of cholinesterase inhibitors and memantine for treating dementia: Evidence review for a clinical practice guideline. Ann Intern Med. 2008;148:379–397
  16. Tariq SH, Tumosa N, Chibnall JT, et al. Comparison of the Saint Louis University mental status examination and the mini-mental state examination for detecting dementia and mild neurocognitive disorder—a pilot study. Am J Geriatr Psychiatry. 2006;14:900–910
  17. Ray WA, Chung CP, Murray KT, et al. Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med. 2009;360:225–235
  18. Schneider LS, Tariot PN, Dagerman KS, et al. Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease. N Engl J Med. 2006;355:1525–1538
  19. Levenson SA, Morley JE. Evidence rocks in long-term care, but does it roll?. J Am Med Dir Assoc. 2007;8:493–501
  20. Beckett NS, Peters R, Fletcher AE, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med. 2008;358:1887–1898
  21. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA. 2002;288:2981–2997
  22. Joseph J, Koka M, Aronow WS. Prevalence of a hemoglobin A1c less than 7.0%, of a blood pressure less than 130/80 mm Hg, and of a serum low-density lipoprotein cholesterol less than 100 mg/dL in older patients with diabetes mellitus in an academic nursing home. J Am Med Dir Assoc. 2008;9:51–54
  23. Skyler JS, Bergenstal R, Bonow RO, et al. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Associaton and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. J Am Coll Cardiol. 2009;53:298–304
  24. Kim MJ, Rolland Y, Cepeda O, et al. Diabetes mellitus in older men. Aging Male. 2006;9:139–147
  25. Mazza AD, Morley JE. Update on diabetes in the elderly and the application of current therapeutics. J Am Med Dir Assoc. 2007;8:489–492
  26. Buckingham RE, Hanna A. Thiazolidinedione insulin sensitizers and the heart: A tale of two organs?. Diabetes Obes Metab. 2008;10:312–328
  27. Schwartz AV. TZDs and bone: A review of the recent clinical evidence. PPAR Res. 2008;2008:297893
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  29. Tariq SH. Constipation in long-term care. J Am Med Dir Assoc. 2007;8:209–218
  30. Bhutto A, Morley JE. The clinical significance of gastrointestinal changes with aging. Curr Opin Clin Nutr Metab Care. 2008;11:651–660
  31. Lawhorne LW, Ouslander JG, Parmelee PA. Urinary Incontinence Work Group of the AMDA-F LTC Research Network. Clinical practice guidelines, process improvement teams, and performance on a quality indicator for urinary incontinence: A pilot study. J Am Med Dir Assoc. 2008;9:504–508
  32. Al-Samarrai NR, Uman GC, Al-Samarrai T, Alessi CA. Introducing a new incontinence management system for nursing home residents. J Am Med Dir Assoc. 2007;8:253–261
  33. Messinger-Rapport BJ, Thomas DR, Gammack JK, Morley JE. Clinical update on nursing home medicine: 2008. J Am Med Dir Assoc. 2008;9:460–475
  34. Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomized controlled trial. Lancet. 2002;360:1623–1630
  35. Gissi-HF Investigators, Tavazzi L, Maggioni AP, et al. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomized, double-blind, placebo-controlled trial. Lancet. 2008;372:1223–1230
  36. Joseph J, Koka M, Aronow WS. Prevalence of use of antiplatelet drugs, beta blockers, statins, and angiontensin-converting enzyme inhibitors or angiotensin receptor blockers in older patients with coronary artery disease in an academic nursing home. J Am Med Dir Assoc. 2008;9:124–127
  37. Abdel-Latif AK, Peng X, Messinger-Rapport BJ. Predictors of anticoagulation prescription in nursing home residents with atrial fibrillation. J Am Med Dir Assoc. 2005;6:128–131
  38. Morley JE. Weight loss in older persons: new therapeutic approaches. Curr Pharm Des. 2007;13:3637–3647
  39. Morley JE, Thomas DR. Cachexia: new advances in the management of wasting diseases. J Am Med Dir Assoc. 2008;9:205–210
  40. Morley JE, Haren MT, Rolland Y, Kim MJ. Frailty. Med Clin North Am. 2006;90:837–847
  41. Messinger-Rapport BJ, Morley JE, Thomas DR, Gammack JK. Intensive session: New approaches to medical issues in long-term care. J Am Med Dir Assoc. 2007;8:421–433
  42. Locca JF, Bula CJ, Zumbach S, Bugnon O. Pharmacological treatment of behavioral and psychological symptoms of dementia (BPSD) in nursing homes: Development of practice recommendations in a Swiss canton. J Am Med Dir Assoc. 2008;9:439–448
  43. Thakur M, Blazer DG. Depression in long-term care. J Am Med Dir Assoc. 2008;9:82–87
  44. Harrington BC, Dickey L, Heiner S. Our experience with proton pump inhibitor (PPI) use in our local long-term care facility. J Am Med Dir Assoc. 2008;9:280–281
  45. Glew CM, Rantler RJ. Use of proton pump inhibitors and other acid suppressive medications in newly admitted nursing facility patients. J Am Med Dir Assoc. 2008;9:280–281

PII: S1525-8610(09)00103-0

doi: 10.1016/j.jamda.2009.03.011

JAMDA
Volume 10, Issue 5 , Pages 289-291 , June 2009

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