Advertisement
JAMDA Online Original Study| Volume 14, ISSUE 8, P627.e7-627.e12, August 2013

Usefulness of 2 Questions About Age and Year of Birth in the Case-Finding of Dementia

  • Tirso Ventura
    Affiliations
    Psychiatry Service, Hospital Universitario Miguel Servet, Zaragoza, Spain

    Department of Medicine and Psychiatry, Universidad de Zaragoza, Zaragoza, Spain

    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain
    Search for articles by this author
  • Concepción De-la-Cámara
    Affiliations
    Department of Medicine and Psychiatry, Universidad de Zaragoza, Zaragoza, Spain

    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain

    Psychiatry Service, Hospital Clínico Universitario, Zaragoza, Spain
    Search for articles by this author
  • Raúl Lopez-Anton
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Department of Psychology and Sociology, Universidad de Zaragoza, Zaragoza, Spain
    Search for articles by this author
  • Javier Santabárbara
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Department of Preventive Medicine and Public Health, Universidad de Zaragoza, Zaragoza, Spain
    Search for articles by this author
  • Guillermo Marcos
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain

    Department of Preventive Medicine and Public Health, Universidad de Zaragoza, Zaragoza, Spain

    Medical Records Service, Hospital Clínico Universitario, Zaragoza, Spain
    Search for articles by this author
  • Miguel Angel Quintanilla
    Affiliations
    Department of Medicine and Psychiatry, Universidad de Zaragoza, Zaragoza, Spain

    Psychiatry Service, Hospital Clínico Universitario, Zaragoza, Spain
    Search for articles by this author
  • Antonio Campayo
    Affiliations
    Department of Medicine and Psychiatry, Universidad de Zaragoza, Zaragoza, Spain

    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain

    Psychiatry Service, Hospital Clínico Universitario, Zaragoza, Spain
    Search for articles by this author
  • Elena Lobo
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Department of Preventive Medicine and Public Health, Universidad de Zaragoza, Zaragoza, Spain
    Search for articles by this author
  • Juan Francisco Roy
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Department of Psychology and Sociology, Universidad de Zaragoza, Zaragoza, Spain
    Search for articles by this author
  • Pedro Saz
    Affiliations
    Department of Medicine and Psychiatry, Universidad de Zaragoza, Zaragoza, Spain

    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain
    Search for articles by this author
  • Beatriz Olaya
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Sant Boi de Llobregat, Barcelona, Spain
    Search for articles by this author
  • Josep María Haro
    Affiliations
    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Sant Boi de Llobregat, Barcelona, Spain
    Search for articles by this author
  • Leocadio Rodríguez-Mañas
    Affiliations
    Hospital Universitario de Getafe, Getafe, Madrid, Spain
    Search for articles by this author
  • Norman Sartorius
    Affiliations
    Association for the Improvement of Mental Health Programmes (AMH), Geneva, Switzerland
    Search for articles by this author
  • Antonio Lobo
    Correspondence
    Address correspondence to Antonio Lobo, MD, PhD, Servicio de Psiquiatría, Hospital Clínico Universitario, planta 3, Avd. San Juan Bosco, 15, 50009 Zaragoza, Spain.
    Affiliations
    Department of Medicine and Psychiatry, Universidad de Zaragoza, Zaragoza, Spain

    Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Ministry of Science and Innovation, Madrid, Spain

    Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain

    Psychiatry Service, Hospital Clínico Universitario, Zaragoza, Spain
    Search for articles by this author

      Abstract

      Objective

      To test the hypothesis that the efficacy of 2 simple questions commonly used in clinical practice, asking the age and year of birth of individuals, will be satisfactory to rule out cases of dementia.

      Design

      Population-based, longitudinal, prospective study focused on the incidence of dementia. In the baseline, a 2-phase procedure for identifying cases and noncases of dementia was implemented.

      Setting

      Zaragoza, Spain.

      Participants

      Individuals 65 years or older without previous diagnoses of dementia (n = 3613) drawn from the population-based random sample of the ZARADEMP project.

      Measurements

      Standardized instruments were used, including the Geriatric Mental State (GMS) and the History and Aetiological Schedule (HAS); cases were diagnosed according to DSM-IV criteria (“reference standard”). The simple cognitive test used in this study consists of the following 2 compulsory questions: “How old are you?” and “What year were you born?”

      Results

      The test was well accepted by the participants and took less than 30 seconds to complete. Compared with the “reference standard,” validity coefficients for incorrect answers in both questions were as follows: sensitivity 61.2%, specificity 97.8%, positive predictive value 44.4%, negative predictive value 98.9%.

      Conclusions

      This ultra-short test has very good specificity and negative predictive power. Its use to rule out cases of dementia might be generalized, as it has the best efficiency reported to date.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of the American Medical Directors Association
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Collins P.Y.
        • Patel V.
        • Joestl S.S.
        • et al.
        Grand challenges in global mental health.
        Nature. 2011; 475: 27-30
        • Mitchell S.L.
        • Black B.S.
        • Ersek M.
        • et al.
        Advanced dementia: State of the art and priorities for the next decade.
        Ann Intern Med. 2012; 156: 45-51
        • Lobo A.
        • Lopez-Anton R.
        • Santabárbara J.
        • et al.
        Incidence and lifetime risk of dementia and Alzheimer's disease in a Southern European population.
        Acta Psychiatr Scand. 2011; 124: 372-383
        • Stephan B.C.
        • Kurth T.
        • Matthews F.E.
        • et al.
        Dementia risk prediction in the population: Are screening models accurate?.
        Nat Rev Neurol. 2010; 6: 318-326
      1. Public health planning for dementia must start now.
        Lancet Neurol. 2012; 11: 477
        • Waldemar G.
        • Phung K.T.
        • Burns A.
        • et al.
        Access to diagnostic evaluation and treatment for dementia in Europe.
        Int J Geriatr Psychiatry. 2007; 22: 47-54
        • Brunet M.D.
        • McCartney M.
        • Heath I.
        • et al.
        There is no evidence base for proposed dementia screening.
        BMJ. 2012; 345: e8588
      2. Screening for Dementia, Topic Page. June 2003. US Preventive Services Task Force. Available at: http://www.uspreventiveservicestaskforce.org/uspstf/uspsdeme.htm. Accessed March 19, 2013.

        • Brayne C.
        • Fox C.
        • Boustani M.
        Dementia screening in primary care: Is it time?.
        JAMA. 2007; 298: 2409-2411
        • Christensen M.D.
        • White H.K.
        Dementia assessment and management.
        J Am Med DirAssoc. 2007; 8: e89-e98
        • Boustani M.
        • Peterson B.
        • Hanson L.
        • et al.
        Screening for dementia in primary care: A summary of the evidence for the U.S. Preventive Services Task Force.
        Ann Intern Med. 2003; 138: 927-937
        • Iliffe S.
        • Robinson L.
        • Brayne C.
        • et al.
        Primary care and dementia: 1. diagnosis, screening and disclosure.
        Int J Geriatr Psychiatry. 2009; 24: 895-901
        • Holsinger T.
        • Deveau J.
        • Boustani M.
        • Williams Jr., J.W.
        Does this patient have dementia?.
        JAMA. 2007; 297: 2391-2394
        • Russ T.C.
        • Shenkin S.D.
        • Reynish E.
        • et al.
        Dementia in acute hospital inpatients: The role of the geriatrician.
        Age Ageing. 2012; 41: 282-284
        • Buntinx F.
        • De Lepeleire J.
        • Paquay L.
        • et al.
        Diagnosing dementia: No easy job.
        BMC Fam Pract. 2011; 12: 60
        • Folstein M.F.
        • Folstein S.E.
        • Mchugh P.R.
        Mini-Mental State. A practical method for grading the cognitive state of patients for the clinician.
        J Psychiatr Res. 1975; 12: 189-198
        • Mitchell A.J.
        • Malladi S.
        Screening and case finding tools for the detection of dementia. Part I: Evidence-based meta-analysis of multidomain tests.
        Am J Geriatr Psychiatry. 2010; 18: 759-782
        • Brodaty H.
        • Low L.
        • Gibson L.
        • Burns K.
        What is the best dementia screening instrument for general practitioners to use?.
        Am J Geriatr Psychiatry. 2006; 14: 391-400
        • Ismail Z.
        • Rajji T.K.
        • Shulman K.I.
        Brief cognitive screening instruments: An update.
        Int J Geriatr Psychiatry. 2010; 25: 111-120
        • Lobo A.
        • Saz P.
        • Marcos G.
        • et al.
        [Revalidation and standardization of the cognition mini-exam (first Spanish version of the Mini-Mental Status Examination) in the general geriatric population].
        Med Clin (Barc). 1999; 112 (Spanish): 767-774
        • Mitchell A.J.
        • Malladi S.
        Screening and case-finding tools for the detection of dementia. Part II: Evidence-based meta-analysis of single-domain tests.
        Am J Geriatr Psychiatry. 2010; 18: 783-800
        • Lobo A.
        • Saz P.
        • Marcos G.
        • et al.
        The ZARADEMP Project on the incidence, prevalence and risk factors of dementia (and depression) in the elderly community: II. Methods and first results.
        Eur J Psychiatry. 2005; 19: 40-54
        • Copeland J.R.
        • Dewey M.E.
        • Wood N.
        • et al.
        Range of mental illness amongst the elderly in the community: Prevalence in Liverpool using the GMS-AGECAT package.
        Br J Psychiatry. 1987; 150: 815-823
        • Lobo A.
        • Saz P.
        • Marcos G.
        • et al.
        The prevalence of dementia and depression in the elderly community in a southern European population. The Zaragoza study.
        Arch Gen Psychiatry. 1995; 52: 497-506
        • Fletcher R.H.
        • Fletcher S.W.
        • Wagner E.H.
        Clinical Epidemiology: The Essentials.
        Lippincott Williams & Wilkins, Philadelphia, PA2005
        • Mitchell A.J.
        • Coyne J.C.
        Do ultra-short screening instruments accurately detect depression in primary care? A pooled analysis and meta-analysis of 22 studies.
        Br J Gen Pract. 2007; 57: 144-151
        • Hirsch C.
        ACP Journal Club. The Mini-Cog had sensitivity similar to the longer 3MS for detecting cognitive impairment or dementia.
        Ann Intern Med. 2012; 157: JC4-JC8
        • Buschke H.
        • Kuslansky G.
        • Katz M.
        • et al.
        Screening for dementia with the memory impairment screen.
        Neurology. 1999; 52: 231-238
        • Kuslansky G.
        • Buschke H.
        • Katz M.
        • et al.
        Screening for Alzheimer's disease: The memory impairment screen versus the conventional three-word memory test.
        J Am Geriatr Soc. 2002; 50: 1086-10891
        • Straus S.E.
        • Richardson W.S.
        • Glasziou P.
        • Haynes R.B.
        Evidence-based Medicine: How to Practice and Teach EBM.
        3rd ed. Churchill Livingstone, Edinburgh, Scotland2005
        • Kansagara D.
        • Freeman M.
        A Systematic Evidence Review of the Signs and Symptoms of Dementia and Brief Cognitive Tests Available in VA.
        Department of Veterans Affairs (US), Washington, DC2010 (Available at:) (Accessed March 19, 2013)
        • Wilson J.M.
        • Jungner Y.G.
        Principles and practice of mass screening for disease.
        WHO, Geneva1968
        • Raymont V.
        • Bingley W.
        • Buchanan A.
        • et al.
        Prevalence of mental incapacity in medical inpatients and associated risk factors: cross-sectional study.
        Lancet. 2004; 364: 1421-1427