Abstract
Objectives
Design
Setting
Participants
Measurements
Results
Conclusions
Keywords
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of the American Medical Directors AssociationReferences
- Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care.J Gerontol A Biol Sci Med Sci. 2004; 59: 255-263
- Ageing populations: The challenges ahead.Lancet. 2009; 374: 1196-1208
- Trajectories of disability in the last year of life.N Engl J Med. 2010; 362: 1173-1180
- The cognitive correlates of functional status: A review from the committee on research of the American Neuropsychiatric association.J Neuropsychiatry Clin Neurosci. 2007; 19: 249-265
- Prognostic value of usual gait speed in well-functioning older people–results from the Health, Aging and Body Composition Study.J Am Geriatr Soc. 2005; 53: 1675-1680
- Lower extremity function and subsequent disability: Consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery.J Gerontol A Biol Sci Med Sci. 2000; 55: M221-M231
- Dementia and dependence: Do modifiable risk factors delay disability?.Neurology. 2014; 82: 1543-1550
- The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.Alzheimers Dement. 2011; 7: 270-279
- Mild cognitive impairment as a diagnostic entity.J Intern Med. 2004; 256: 183-194
- Clinical practice. Mild cognitive impairment.N Engl J Med. 2011; 364: 2227-2234
- The advanced activities of daily living: A tool allowing the evaluation of subtle functional decline in mild cognitive impairment.J Nutr Health Aging. 2013; 17: 64-71
- Mild cognitive impairment and everyday function: Evidence of reduced speed in performing instrumental activities of daily living.Am J Geriatr Psychiatry. 2008; 16: 416-424
- Mild cognitive impairment and 10-year trajectories of disability in the Iowa Established Populations for Epidemiologic Studies of the Elderly cohort.J Am Geriatr Soc. 2005; 53: 1966-1972
- Mild cognitive impairment in a community sample: The Sydney Memory and Ageing Study.Alzheimers Dement. 2013; 9: 310-317
- The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese.Alzheimers Dement. 2014; 10: 439-447
- Combined prevalence of frailty and mild cognitive impairment in a population of elderly Japanese people.J Am Med Dir Assoc. 2013; 14: 518-524
- Prevalence, distribution, and impact of mild cognitive impairment in Latin America, China, and India: A10/66 population-based study.PLoS Med. 2012; 9: e1001170
- Gait dysfunction in mild cognitive impairment syndromes.J Am Geriatr Soc. 2008; 56: 1244-1251
- Assessing the temporal relationship between cognition and gait: Slow gait predicts cognitive decline in the Mayo Clinic Study of Aging.J Gerontol A Biol Sci Med Sci. 2013; 68: 929-937
- The trajectory of gait speed preceding mild cognitive impairment.Arch Neurol. 2010; 67: 980-986
- Frailty syndrome and the risk of vascular dementia: The Italian Longitudinal Study on Aging.Alzheimers Dement. 2013; 9: 113-122
- Association of brain pathology with the progression of frailty in older adults.Neurology. 2013; 80: 2055-2061
- Motoric cognitive risk syndrome and the risk of dementia.J Gerontol A Biol Sci Med Sci. 2013; 68: 412-418
- Motoric cognitive risk syndrome: Multicountry prevalence and dementia risk.Neurology. 2014; 83: 718-726
- Gait slowing as a predictor of incident dementia: 6-Year longitudinal data from the Sydney older persons study.J Neurol Sci. 2005; 229–230: 89-93
- Disability in older adults: Evidence regarding significance, etiology, and risk.J Am Geriatr Soc. 1997; 45: 92-100
- Cognitive function and falling among older adults with mild cognitive impairment and slow gait.Geriatr Gerontol Int. 2015; 15: 1073-1078
- What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function.J Gerontol A Biol Sci Med Sci. 2013; 68: 409-411
- Population ageing and wellbeing: Lessons from Japan's long-term care insurance policy.Lancet. 2011; 378: 1183-1192
- “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician.J Psychiatr Res. 1975; 12: 189-198
- Evaluation of multidimensional neurocognitive function using a tablet personal computer: Test-retest reliability and validity in community-dwelling older adults.Geriatr Gerontol Int. 2013; 13: 860-866
- Performance-based assessments and demand for personal care in older japanese people: A cross-sectional study.BMJ Open. 2013; 3: e002424
- Care-needs certification in the long-term care insurance system of Japan.J Am Geriatr Soc. 2005; 53: 522-527
- Japan's universal long-term care system reform of 2005: Containing costs and realizing a vision.J Am Geriatr Soc. 2007; 55: 1458-1463
- Association of insulin-like growth factor-1 with mild cognitive impairment and slow gait speed.Neurobiol Aging. 2015; 36: 942-947
- Geriatric depression scale.Psychopharmacol Bull. 1988; 24: 709-711
- Gait speed and survival in older adults.JAMA. 2011; 305: 50-58
- Mild cognitive impairment status and mobility performance: An analysis from the Boston RISE Study.J Gerontol A Biol Sci Med Sci. 2014; 69: 1511-1518
- Neuroimaging of mobility in aging: A targeted review.J Gerontol A Biol Sci Med Sci. 2014; 69: 1375-1388
- Motor control and aging: Links to age-related brain structural, functional, and biochemical effects.Neurosci Biobehav Rev. 2010; 34: 721-733
- Slow gait in MCI is associated with ventricular enlargement: Results from the Gait and Brain Study.J Neural Transm. 2013; 120: 1083-1092
- Motor cortex and gait in mild cognitive impairment: A magnetic resonance spectroscopy and volumetric imaging study.Brain. 2013; 136: 859-871
- Can performance on daily activities discriminate between older adults with normal cognitive function and those with mild cognitive impairment?.J Am Geriatr Soc. 2014; 62: 1347-1352
- Functional, global and cognitive decline correlates to accumulation of Alzheimer's pathology in MCI and AD.Curr Alzheimer Res. 2010; 7: 280-286
- Executive function and instrumental activities of daily living in mild cognitive impairment and Alzheimer's disease.Alzheimers Dement. 2011; 7: 300-308
- Patterns and predictors of recovery from exhaustion in older adults: The cardiovascular health study.J Am Geriatr Soc. 2011; 59: 207-213
- Gait and cognition: A complementary approach to understanding brain function and the risk of falling.J Am Geriatr Soc. 2012; 60: 2127-2136
- Impairments in physical performance and cognitive status as predisposing factors for functional dependence among nondisabled older persons.J Gerontol A Biol Sci Med Sci. 1996; 51: M283-M288
- Cognitive function and gait speed under normal and dual-task walking among older adults with mild cognitive impairment.BMC Neurol. 2014; 14: 67
- Age-related differences in attentional cost associated with postural dual tasks: Increased recruitment of generic cognitive resources in older adults.Neurosci Biobehav Rev. 2013; 37: 1824-1837
- Cognitive motor interference while walking: A systematic review and meta-analysis.Neurosci Biobehav Rev. 2011; 35: 715-728
- Do changes in circulating biomarkers track with each other and with functional changes in older adults?.J Gerontol A Biol Sci Med Sci. 2014; 69: 174-181
- Inflammatory markers in population studies of aging.Ageing Res Rev. 2011; 10: 319-329
Article info
Publication history
Footnotes
This work was supported by Health and Labor Sciences Research Grants (Comprehensive Research on Aging and Health); a Grant-in-Aid for Scientific Research (B) (grant number 23300205); a Grant-in-Aid for Young Scientists (A) (grant number 15H05369) and Research Funding for Longevity Sciences (22-16).
The authors declare no conflicts of interest.