Mild cognitive impairment (MCI) may be a risk for disability, and co-occurrence of slow gait (SG) and MCI may increase this risk.
The study included 3482 older adults (mean age: 71.4 years) without disability at baseline.
We collected information on demographic variables, measured gait speed and cognitive function to diagnose MCI at baseline. During the follow-up period, the incident disability was monitored. Participants were divided into groups without MCI and SG (control), with SG without MCI (SG), without SG and with MCI in single (sMCI) or multiple (mMCI) domains, and with SG and MCI in single (sMCI + SG) and multiple (mMCI + SG) domains.
During follow-up, 134 participants developed disability (mean follow-up: 29.4 months). The proportions of incident disability were higher in the MCI with SG, MCI, and SG groups, compared with the control group. SG [hazard ratio 2.27 (95% confidence interval: 1.38–3.73)], mMCI [2.56 (1.31–5.02)], sMCI + SG [2.46 (1.21–5.00)], and mMCI + SG [3.48 (1.79–6.76)] participants had risks for disability.
Co-occurrence of SG and MCI in multiple domains has a higher risk of disability than each condition alone.
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Published online: August 19, 2015
This work was supported by Health and Labor Sciences Research Grants (Comprehensive Research on Aging and Health); a Grant-in-Aid for Scientific Research (B) (grant number 23300205); a Grant-in-Aid for Young Scientists (A) (grant number 15H05369) and Research Funding for Longevity Sciences (22-16).
The authors declare no conflicts of interest.
© 2015 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.