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Special Article| Volume 19, ISSUE 3, P193-199, March 2018

Research Priorities for Optimizing Geriatric Pharmacotherapy: An International Consensus

  • Edwin C.K. Tan
    Correspondence
    Address correspondence to Edwin C.K. Tan PhD, Center for Medicine Use and Safety Faculty of Pharmacy and Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade, Parkville, VIC 3052, Australia.
    Affiliations
    Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Australia

    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
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  • Janet K. Sluggett
    Affiliations
    Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Australia

    NHMRC Cognitive Decline Partnership Center, Hornsby Ku-ring-gai Hospital, Hornsby, NSW, Australia
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  • Kristina Johnell
    Affiliations
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
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  • Graziano Onder
    Affiliations
    Department of Geriatrics, Università Cattolica del Sacro Cuore, Rome, Italy
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  • Monique Elseviers
    Affiliations
    Center for Research and Innovation in Care (CRIC), University of Antwerp, Antwerp, Belgium

    Department of Clinical Pharmacology, University of Ghent, Ghent, Belgium
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  • Lucas Morin
    Affiliations
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
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  • Davide L. Vetrano
    Affiliations
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden

    Department of Geriatrics, Università Cattolica del Sacro Cuore, Rome, Italy
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  • Jonas W. Wastesson
    Affiliations
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
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  • Johan Fastbom
    Affiliations
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
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  • Heidi Taipale
    Affiliations
    Kuopio Research Center of Geriatric Care, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland

    Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
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  • Antti Tanskanen
    Affiliations
    Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
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  • J. Simon Bell
    Affiliations
    Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Australia

    NHMRC Cognitive Decline Partnership Center, Hornsby Ku-ring-gai Hospital, Hornsby, NSW, Australia

    Kuopio Research Center of Geriatric Care, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland
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  • on behalf of theOptimizing Geriatric Pharmacotherapy through Pharmacoepidemiology Network (OPPEN) Group
Published:January 18, 2018DOI:https://doi.org/10.1016/j.jamda.2017.12.002

      Abstract

      Medication management is becoming increasingly challenging for older people, and there is limited evidence to guide medication prescribing and administration for people with multimorbidity, frailty, or at the end of life. Currently, there is a lack of clear research priorities in the field of geriatric pharmacotherapy. To address this issue, international experts from 5 research groups in geriatric pharmacotherapy and pharmacoepidemiology research were invited to attend the inaugural Optimizing Geriatric Pharmacotherapy through Pharmacoepidemiology Network workshop. A modified nominal group technique was used to explore and consolidate the priorities for conducting research in this field. Eight research priorities were elucidated: quality of medication use; vulnerable patient groups; polypharmacy and multimorbidity; person-centered practice and research; deprescribing; methodological development; variability in medication use; and national and international comparative research. The research priorities are discussed in detail in this article with examples of current gaps and future actions presented. These priorities highlight areas for future research in geriatric pharmacotherapy to improve medication outcomes in older people.

      Keywords

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