Advertisement

Receptive Music Therapy Is More Effective than Interactive Music Therapy to Relieve Behavioral and Psychological Symptoms of Dementia: A Systematic Review and Meta-Analysis

Published:February 04, 2018DOI:https://doi.org/10.1016/j.jamda.2017.12.009

      Abstract

      Background

      Music therapy is demonstrated to be effective to relieve the agitation among people with dementia, but the comparative effectiveness of methods of music engagement for people with dementia is uncertain.

      Objective

      To evaluate the effects on cognitive functions and behavioral symptoms between interactive and receptive music therapies for people with dementia.

      Methods

      Prospective studies evaluating interactive and receptive music therapies were identified from the OVID databases, included MEDLINE, EMBASE, PsycINFO, and CINAHL. Supplementary search was conducted in Google Scholar. The primary outcome focused on cognitive function; the secondary outcomes were apathy, anxiety, depressive symptoms, agitation, and other behavioral problems. All outcomes were measured by the standard assessment tools. The heterogeneity of studies was examined, and the effects were pooled by meta-analysis. Quality of studies and risk of bias were assessed.

      Results

      Thirty-eight trials involving 1418 participants with dementia were included. The mean age ranged from 75 to 90 years, and the percentage of male participants ranged from 6% to 83%. No significant difference was found between participants receiving interactive or receptive music therapy and usual care in cognitive function; the mean difference (MD) of Mini-Mental State Examination was 0.18 [95% confidence interval (CI) −1.34 to 1.69], and −0.15 (95% CI −0.55 to 0.25), respectively. Participants with receptive music therapy had significant decrease in agitation (Cohen-Mansfield Agitation Inventory: MD = −7.99, 95% CI −5.11 to −0.87) and behavioral problems (Neuropsychiatric Inventory: MD = −3.02 95% CI −5.90 to −0.15) compared to usual care, while no significant difference was found between interactive music therapy and usual care in behavioral problems and psychiatric symptoms.

      Conclusions

      This study demonstrated that receptive music therapy could reduce agitation, behavioral problems, and anxiety in older people with dementia, and appears to be more effective than interactive music therapy. It is easy and convenient to implement receptive music therapy; therefore, we recommended the use of receptive music therapy in nursing homes, day care centers, and client homes.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of the American Medical Directors Association
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • World Health Organization
        Dementia Fact Sheet.
        (Available at:)
        • Hansen R.A.
        • Gartlehner G.
        • Webb A.P.
        • et al.
        Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: A systematic review and meta-analysis.
        Clin Interv Aging. 2008; 3: 211-225
        • Tsoi K.K.F.
        • Chan J.Y.C.
        • Leung N.W.Y.
        • et al.
        Combination therapy showed limited superiority over monotherapy for Alzheimer’s disease: A meta-analysis of 14 randomized trials.
        J Am Med Dir Assoc. 2016; 17: 863.e1-863.e8
        • Sepehry A.A.
        • Lee P.E.
        • Hsiung G.Y.
        • et al.
        Effect of selective serotonin reuptake inhibitors in Alzheimer's disease with comorbid depression: A meta-analysis of depression and cognitive outcomes.
        Drugs Aging. 2012; 29: 793-806
        • Ballard C.
        • Margallo-Lana M.
        • Juszczak E.
        • et al.
        Quetiapine and rivastigmine and cognitive decline in Alzheimer’s disease: Randomised double blind placebo controlled trial.
        BMJ. 2005; 330: 874
        • Schneider L.S.
        • Dagerman K.S.
        • Insel P.
        Risk of death with atypical antipsychotic drug treatment for dementia: Meta-analysis of randomized placebo-controlled trials.
        JAMA. 2005; 294: 1934-1943
        • Ballard C.
        • Howard R.
        Neuroleptic drugs in dementia: Benefits and harm.
        Nat Rev Neurosci. 2006; 7: 492-500
        • Pedersen S.K.A.
        • Andersen P.N.
        • Lugo R.G.
        • et al.
        Effects of music on agitation in dementia: A meta-analysis.
        Front Psychol. 2017; 8: 742
        • Hill N.T.
        • Mowszowski L.
        • Naismith S.L.
        • et al.
        Computerized cognitive training in older adults with mild cognitive impairment or dementia: A systematic review and meta-analysis.
        Am J Psychiatry. 2017; 174: 329-340
        • Brett L.
        • Traynor V.
        • Stapley P.E.
        Effects of physical exercise on health and well-being of individuals living with a dementia in nursing homes: A systematic review.
        J Am Med Dir Assoc. 2016; 17: 104-116
        • Orgeta V.
        • Qazi A.
        • Spector A.
        • Orrell M.
        Psychological treatments for depression and anxiety in dementia and mild cognitive impairment: Systematic review and meta-analysis.
        Br J Psychiatry. 2015; 207: 293-298
        • Olazarán J.
        • Reisberg B.
        • Clare L.
        • et al.
        Nonpharmacological therapies in Alzheimer’s disease: A systematic review of efficacy.
        Dement Geriatr Cogn Disord. 2010; 30: 161-178
        • Ueda T.
        • Suzukamo Y.
        • Sato M.
        • et al.
        Effects of music therapy on behavioral and psychological symptoms of dementia: A systematic review and meta-analysis.
        Ageing Res Rev. 2012; 2: 628-641
        • Zhang Y.
        • Cai J.
        • An L.
        • et al.
        Does music therapy enhance behavioral and cognitive function in elderly dementia patients? A systematic review and meta-analysis.
        Ageing Res Rev. 2017; 35: 1-11
        • Chang Y.S.
        • Chu H.
        • Yang C.Y.
        • et al.
        The efficacy of music therapy for people with dementia: A meta-analysis of randomised controlled trials.
        J Clin Nurs. 2015; 24: 3425-3440
        • van der Steen J.T.
        • van Soest-Poortvliet M.C.
        • van der Wouden J.C.
        • et al.
        Music-based therapeutic interventions for people with dementia.
        Cochrane Database Syst Rev. 2017; 5: CD003477
        • Vasionytė I.
        • Madison G.
        Musical intervention for patients with dementia: A meta-analysis.
        J Clin Nurs. 2013; 22: 1203-1216
        • Moher D.
        • Liberati A.
        • Tetzlaff J.
        • Altman D.G.
        • PRISMA Group
        Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement.
        Ann Intern Med. 2009; 151: 264-269
        • Cohen-Mansfield J.
        • Marx M.
        • Rosenthal A.S.
        A description of agitation in a nursing home.
        J Gerontol. 1989; 44: 77-84
        • Folstein M.F.
        • Folstein S.E.
        • McHugh P.R.
        “Mini-Mental State”. A practical method for grading the cognitive state of patients for the clinician.
        J Psychiatr Res. 1975; 12: 189-198
        • Cummings J.L.
        • Mega M.
        • Gray K.
        • et al.
        The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia.
        Neurology. 1994; 44: 2308-2314
        • Shankar K.K.
        • Walker M.
        • Frost D.
        • et al.
        The development of a valid and reliable scale for rating anxiety in dementia (RAID).
        Aging Mental Health. 1999; 3: 39-49
        • Yesavage J.A.
        • Brink T.L.
        • Rose T.L.
        • et al.
        Development and validation of the geriatric depression scale: A preliminary report.
        J Psychiatr Res. 1983; 17: 37-49
        • Higgins J.P.
        • Altman D.G.
        • Gotzsche D.M.
        • et al.
        The Cochrane collaboration’s tool for assessing risk of bias in randomised trials.
        BMJ. 2011; 343: d5928
        • Moher D.
        • Schulz K.F.
        • Altman D.G.
        The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomised trials.
        Lancet. 2001; 357: 1191-1194
      1. Review Manager (RevMan) [Computer program]. Version 5.3. The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen2014
        • Fleiss J.L.
        Analysis of data from multiclinic trials.
        Control Clin Trials. 1986; 7: 267-275
        • DerSimonian R.
        • Laird N.
        Meta-analysis in clinical trials.
        Control Clin Trials. 1986; 7: 177-188
        • Sung H.C.
        • Chang A.M.
        • Abbey J.
        The effects of preferred music on agitation of older people with dementia in Taiwan.
        Int J Geriatr Psychiatry. 2006; 21: 999-1000
        • Gerdner L.A.
        Effects of individualized versus classical ‘relaxation’ music on the frequency of agitation in elderly persons with Alzheimer’s disease and related disorders.
        Int Psychogeriatr. 2000; 1: 49-65
        • Arroyo-Anlló E.M.
        • Díaz J.P.
        • Gil R.
        Familiar music as an enhancer of self-consciousness in patients with Alzheimer’s disease.
        Biomed Res Int. 2013; 2013: 752965
        • Sung H.C.
        • Chang A.M.
        • Lee W.L.
        A preferred music listening intervention to reduce anxiety in older adults with dementia in nursing homes.
        J Clin Nurs. 2010; 19: 1056-1064
        • Remington R.
        Calming music and hand massage with agitated elderly.
        Nurs Res. 2002; 51: 317-323
        • Raglio A.
        • Bellandi D.
        • Baiardi P.
        • et al.
        Effect of active music therapy and individualized listening to music on dementia: A multicenter randomized controlled trial.
        J Am Geriatr Soc. 2015; 63: 1534-1539
        • Hicks-Moore S.L.
        • Robinson B.A.
        Favorite music and hand massage. Two interventions to decrease agitation in residents with dementia.
        Dementia. 2008; 7: 95-108