Abstract
Background
Dietary protein intake is inversely associated with physical frailty risk. However,
it is unknown whether an association exists between dietary protein intake and comprehensive
frailty.
Objective
To evaluate the association between protein intake and comprehensive frailty in older
Japanese adults.
Design, setting and participants
This cross-sectional study included 5638 Japanese participants (2707 men and 2931
women) aged ≥65 years from Kameoka City, Kyoto, Japan.
Measurements
Dietary intake was estimated using a validated self-administered food frequency questionnaire.
Comprehensive frailty was assessed using a 25-item Kihon Checklist (KCL), which comprised
instrumental activities of daily living, mobility disability, malnutrition, oral or
eating function, socialization and housebound, cognitive function, and depression
domains. A KCL score of 4 to 6 was defined as prefrailty, and ≥7 as frailty.
Results
In women, but not in men, protein intake showed a lower prevalence for prefrailty
(Q1-Q4, 40.2%, 34.3%, 34.3%, and 36.0%). Higher protein intake was associated with
lower prevalence of frailty both in men (32.5%, 28.4%, 28.3%, and 27.3%) and women
(35.7%, 31.4%, 27.6%, and 28.2%). Moreover, higher dietary protein intake decreased
the odds ratio (OR) for frailty after adjustment for potential confounding factors
in both men (OR for highest vs lowest quartile, 0.62; 95% CI, 0.43-0.89; P for trend = 0.016) and women (OR 0.64; 95% CI, 0.45-0.91; P for trend = 0.017).
Conclusions/implications
The higher dietary protein intake may be inversely associated with the prevalence
of comprehensive frailty in Japanese men and women. Future studies are needed to examine
associations of dietary protein intake within KCL domains.
Keywords
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Article info
Publication history
Published online: May 31, 2018
Footnotes
The authors declare no conflicts of interest.
Identification
Copyright
© 2018 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
