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Letter to the Editor| Volume 19, ISSUE 12, P1135-1136, December 2018

Development and Validation of the Perceptions, Attitudes, and Challenges of Physicians Towards Deprescribing (PACPD-12) Questionnaire

Published:August 30, 2018DOI:https://doi.org/10.1016/j.jamda.2018.07.010
      An ideal holistic health care model, where an apt, cost-effective and well-timed medicine is available and the patient is fittingly counseled on his or her medications, is still a fantasy to most of the common people in a developing country. Factors like inappropriate medication use, polypharmacy, intentional and nonintentional nonadherence to medications, high drug costs, present barriers to ideal patient care.
      • Reeve E.
      • Shakib S.
      • Hendrix I.
      • et al.
      Development and validation of the Patients' Attitudes Towards Deprescribing (PATD) questionnaire.
      • Fick D.M.
      • Mion L.C.
      • Beers M.H.
      • Waller L.J.
      Health outcomes associated with potentially inappropriate medication use in older adults.
      • Kutner J.S.
      • Blatchford P.J.
      • Taylor D.H.
      • et al.
      Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: A randomized clinical trial.
      • Eveleigh R.
      • Grutters J.
      • Muskens E.
      • et al.
      Cost-utility analysis of a treatment advice to discontinue inappropriate long-term antidepressant use in primary care.
      The complex process of deprescribing is gaining merit as one of the tools that can reduce the incidence of the previously mentioned issues. In spite of the documented efficacy of deprescribing in improving patients' outcomes,
      • Iyer S.
      • Naganathan V.
      • McLachlan A.J.
      • Le Conteur D.G.
      Medication withdrawal trials in people aged 65 years and older.
      • Gnjidic D.
      • Le Couteur D.G.
      • Kouladjian L.
      • Hilmer S.N.
      Deprescribing trials: Methods to reduce polypharmacy and the impact on prescribing and clinical outcomes.
      • Page A.T.
      • Clifford R.M.
      • Potter K.
      • et al.
      The feasibility and effect of deprescribing in older adults on mortality and health: A systematic review and meta-analysis.
      • Johansson T.
      • Abuzahra M.E.
      • Keller S.
      • et al.
      Impact of strategies to reduce polypharmacy on clinically relevant endpoints: A systematic review and meta-analysis.
      • Cooper J.A.
      • Cadogan C.A.
      • Patterson S.M.
      • et al.
      Interventions to improve the appropriate use of polypharmacy in older people: A Cochrane systematic review.
      its utility still remains lagging. The suboptimal use of deprescribing can stem from both patient- and prescriber-related factors. Our study aimed at developing and validating a novel questionnaire, thus offering the opportunity to correct the shortcomings in the current system. Because there are no standard questionnaires currently available to explore the prestated area, the Perceptions, Attitudes, and Challenges of Physicians towards Deprescribing (PACPD-12) questionnaire has large potential as an exploratory tool.
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