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This research was funded in part by the Canadian Frailty Network grant SIG2014-M1 (known previously as Technology Evaluation in the Elderly Network, TVN), supported by the Government of Canada through Networks of Centers of Excellence (NCE) Program, and also the Canadian Institutes of Health Research (CIHR) through operating grant MOP-136854. This study was also supported by the Institute for Clinical Evaluative Sciences (ICES), which is funded by an annual grant from the Ontario Ministry of Health and Long-Term Care (MOHLTC). The opinions, results and conclusions reported are those of the authors and are independent from the funding sources. No endorsement by ICES or the Ontario MOHLTC is intended or should be inferred. Parts of this material are based on data and information compiled and provided by the Canadian Institute for Health Information (CIHI). However, the analyses, conclusions, opinions, and statements expressed herein are those of the author, and not necessarily those of CIHI. We thank IMS Brogan Inc. for use of their Drug Information Database.
The Sunnybrook Health Sciences Center Research Ethics Board approved this study, which was conducted according to the rigorous privacy and confidentiality safeguards at ICES.
All authors meet the criteria for authorship stated in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals.
The study sponsors provided the operating costs and infrastructure to support the research. No funding bodies had any role in the study design, data collection, analysis, decision to publish, or preparation of the manuscript.
The authors declare no conflicts of interest.