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This work was supported by the Dunhill Medical Trust (grant number R434/0715 D to DL) and the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care Oxford at Oxford Health NHS Foundation Trust. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. The financial sponsors played no part in the design, execution, analysis and interpretation of data, or writing of the study.
The authors declare no conflicts of interest.