Abstract
Objectives
To identify clinical and/or functional variables predictive of successful oxygen-weaning
among older patients affected by respiratory insufficiency undergoing pulmonary rehabilitation.
Design
Retrospective study.
Setting and Participants
Data are from 154 patients aged 65 years and older (mean age = 78.1 years; female
50.6%) admitted to a pulmonary rehabilitation unit to follow an in-patient program.
Patients must require oxygen therapy at admission.
Methods
All patients performed the 6-Minute Walking Test at admission and before discharge
as well as a spirometry at a steady state. Multivariate logistic regressions were
performed to identify positive and negative predictors of successful oxygen weaning.
Results
Successful oxygen weaning was obtained in 47 participants (30.5%). The restrictive
pattern was associated with a 4-fold likelihood of successful oxygen weaning at the
end of the rehabilitation program compared with the obstructive one. A positive association
was also found for arterial oxygenation index (PaO2/FiO2 ratio) at baseline. A decreased likelihood of successful oxygen weaning was reported
for the subjective dyspnea perception score at exertion evaluated with a modified
Borg scale.
Conclusions and Implications
The restrictive pattern, PaO2/FiO2 ratio, and modified Borg dyspnea scale score under exertion were significantly associated
with successful oxygen-weaning. The identified predictors may support clinicians at
precociously identifying patients who may not require oxygen therapy after discharge.
Therefore, these findings would make it possible for clinicians to better tailor the
rehabilitation program.
Keywords
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Article info
Publication history
Published online: March 12, 2020
Footnotes
T.N. and L.O. contributed equally to this work
This research did not receive any funding from agencies in the public, commercial, or not-for-profit sectors.
The authors declare no conflicts of interest.
Identification
Copyright
© 2020 Published by Elsevier Inc. on behalf of AMDA - The Society for Post-Acute and Long-Term Care Medicine.
