Abstract
Background
The European Working Group on Sarcopenia in Older People (EWGSOP2) recently updated
the definition of sarcopenia in order to reflect scientific and clinical evidences.
Objective
The aim is to explore the prevalence of sarcopenia (according to the new EWGSOP2 definition)
and related risk factors among an unselected sample of subjects living in community.
Setting and Participants
The Longevity Check-up 7+ project is an ongoing cross-sectional study started in June
2015 and conducted in unconventional settings (ie, exhibitions, malls, and health
promotion campaigns). Candidate participants are eligible for enrollment if they are
at least 18 years of age.
Methods
Muscle strength was assessed by handgrip strength and physical performance was evaluated
by chair stand test.
Results
The mean age of 11,253 subjects was 55.6 (standard deviation 11.5, from 18 to 98 years)
years, and 6356 (56%) were women. Using the EWGSOP2 algorithm, 973 participants (8.6%)
were identified as affected by sarcopenia, and the prevalence of sarcopenia significantly
increased with age. Sarcopenia was associated with diabetes prevalence ratio (PR)
1.42, 95% confidence interval (CI) 1.06-1.89, impairment in 400-m walking performance
(PR 2.16, 95% CI 1.74-2.17), and self-reported unhealthy status (PR 1.77, 95% CI 1.45-2.17).
Conversely, a decreased probability of being sarcopenic was detected among subjects
following a healthy diet (PR 0.79, 95% CI 0.63-0.98) and involved in regular physical
activity (PR 0.79, 95% CI 0.64-0.99).
Conclusions and Implications
Muscle strength and physical performance assessment should be considered as the recommended
methods for the early detection of individuals at risk of probable sarcopenia.
Keywords
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Article info
Publication history
Published online: April 28, 2020
Footnotes
The Look-Up 7+ Study Group is composed as follows: Steering Committee: F. Landi, R. Bernabei, Coordinators: E. Marzetti, R. Calvani, L. Mariotti; Writing panel: A.M. Martone, M. D’Angelo, E. Serafini, A. Picca, V. Palmieri, M. Tosato, P. Abete, A. Cherubini, F. Corica, S. Salini; Field investigators: M. Bianco, D. Biscotti, V. Brandi, M. Broccatelli, L. Catalano, F. Ciciarello, M. D’Elia, G. Savera, M. B. Zazzera; Participants: A. Almohani, F. Benvenuto, M. Bianchi, G. Bramato, R. Capitani, C. Celesti, G. Colloca, F. Cuccaro, L. Damato, E. Di Murru, S. Fabrizi, M.T. Fuga, D. Fusco, A. Galliani, V. Galluzzo, S. Gervasi, R. Quarta, G. Modica, R. Monti, E. Ortolani, S. Orvieto, C. Pais, C. Pantanelli, S. Rocchi, D. Ronconi, E. Rota, F. Sollazzo, M. Tritto.
Carni Sostenibili, Danone Italia, Errekappa, Ferrarini, Italfarmaco, Italia Longeva, IVSI, Laborest, Yakult, Marche Region, Nutricia, ProAction, Serenissima, and Novartis supported the Lookup 7+ project. The study was also partly supported by intramural research grants from the Univerità Cattolica del Sacro Cuore (D3.2 2013 and D3.2 2015) to FL and by the non-profit research foundation “Centro Studi Achille e Linda Lorenzon.”
The authors declare no conflicts of interest.
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© 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
