Abstract
Objective
To investigate administration of pro re nata (PRN) medications and nurse-initiated
medications (NIMs) in Australian aged care services over a 12-month period.
Design
Twelve-month longitudinal audit of medication administrations.
Setting and participants
Three hundred ninety-two residents of 10 aged care services in regional Victoria,
Australia.
Methods
Records of PRN and NIM administration were extracted from electronic and hard copy
medication charts. Descriptive statistics were used to calculate medication administration
per person-month. Poisson regression was used to estimate predictors of PRN administration.
Results
Over a median follow-up of 12 months (interquartile range 10–12 months), 93% of residents
were administered a PRN medication and 41% of residents an NIM on 21,147 and 552 occasions,
respectively. The mean number of any PRN administration was 5.85 per person-month.
The most frequently administered PRN medications per person-month were opioids 1.54,
laxatives 0.96, benzodiazepines 0.72, antipsychotics 0.48, paracetamol 0.46, and topical
preparations 0.42. Three-quarters of residents prescribed a PRN opioid or PRN benzodiazepine
and two-thirds of residents prescribed a PRN antipsychotic had the medication administered
on 1 or more occasions over the follow-up.
Conclusions and Implications
Most residents were administered PRN medications. Administration was in line with
Australian regulations and institutional protocols. However, the high frequency of
PRN analgesic, laxative, and psychotropic medication administration highlights the
need for regular clinical review to ensure ongoing safe and appropriate use.
Keywords
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References
- Medication management policy, practice and research in Australian residential aged care: Current and future directions.Pharmacol Res. 2017; 116: 20-28
- Prevalence and factors associated with polypharmacy in long-term care facilities: A systematic review.J Am Med Dir Assoc. 2015; 16 (e1–12): 535
- Frequency of and factors related to pro re nata (PRN) medication use in aged care services.Res Social Adm Pharm. 2018; 14: 964-967
- Guiding principles for medication management in residential aged care facilities.(Available at:)http://www.health.gov.au/internet/main/publishing.nsf/Content/guide-med-mgmt-aged-careDate: 2012Date accessed: April 9, 2020
- Pro re nata (as needed) medication in nursing homes: The longer you stay, the more you get?.Eur J Clin Pharmacol. 2016; 72: 995-1001
- Medication prescribing and administration in nursing homes.Age Ageing. 1998; 27: 385-392
- Factors influencing PRN medication use in nursing homes.Pharm World Sci. 2004; 26: 148-154
- Review of national aged care quality regulatory processes.(Available at:)https://www.health.gov.au/sites/default/files/review-of-national-aged-care-quality-regulatory-processes-report.pdfDate: 2017Date accessed: April 9, 2020
- The Oakden Report.(Available at:)https://www.sahealth.sa.gov.au/wps/wcm/connect/4ae57e8040d7d0d58d52af3ee9bece4b/Oakden+Report+Final+Email+Version.pdfDate: 2017Date accessed: April 9, 2020
- Royal Commission into Aged Care Quality and Safety. Interim Report: Neglect. Volume 1. Chapter 8. Canberra: Commonweath of Australia.(Available at:)https://agedcare.royalcommission.gov.au/publications/Documents/interim-report/interim-report-volume-1.pdfDate: 2019Date accessed: April 9, 2020
- Analgesic use and daytime sleepiness in residents with and without dementia in residential aged care facilities.Drugs Aging. 2015; 32: 1045-1053
- Adverse drug effects in elderly people—a disparity between clinical examination and adverse effects self-reported by the patient.Eur J Clin Pharmacol. 2007; 63: 509-515
- Patient safety and pro re nata prescription and administration: A systematic review.Pharmacy (Basel). 2018; 6
- Pro re nata drug use in nursing home residents: A systematic review.J Am Med Dir Assoc. 2019; 20: 287-293
- ‘As required’ medication regimens for seriously mentally ill people in hospital.Cochrane Database Syst Rev. 2015; : CD003441
- Nurses' attitudes towards the use of PRN psychotropic medications in acute and forensic mental health settings.Int J Ment Health Nurs. 2018; 27: 168-177
- EpiData - comprehensive data management and basic statistical analysis system. 4.4.2.1 ed. Odense Denmark.in: Christiansen T.B. Lauritsen J.M. EpiData Association, 2010 (Available at:)http://www.epidata.dkDate accessed: April 9, 2020
- Process, impact and outcomes of medication review in Australian residential aged care facilities: A systematic review.Australas J Ageing. 2019; 38: 9-25
- Systematic review of the prevalence of medication errors resulting in hospitalization and death of nursing home residents.J Am Geriatr Soc. 2017; 65: 433-442
- Both new and chronic potentially inappropriate medications continued at hospital discharge are associated with increased risk of adverse events.J Am Geriatr Soc. 2020; 68: 1184-1192
- An iceberg phenomenon in dementia: Pain.J Geriatr Psychiatry Neurol. 2018; 31: 186-193
- Guide to the pharmacological management of end of life (terminal) symptoms in residential aged care residents.(Available at:)
- American Geriatrics Society Panel on the Pharmacological Management of Persistent Pain in Older Persons. Pharmacological management of Persistent pain in older persons.J Am Geriatr Soc. 2009; 57: 1331-1346
- AMH aged care companion (online).Australian Medicines Handbook Pty Ltd, Adelaide2019 (Available at:)https://agedcare.amh.net.au/Date accessed: April 9, 2020
- Medical care of older persons in residential aged care facilities.(Available at:)
- Antipsychotic drug use in nursing home residents with and without dementia: Keep an eye on the pro re nata medication.Int Clin Psychopharmacol. 2017; 32: 213-218
- The association between benzodiazepine use and sleep quality in residential aged care facilities: A cross-sectional study.BMC Geriatr. 2016; 16: 196
Article info
Publication history
Published online: June 28, 2020
Footnotes
BA and LMC are employed by health services overseen by the Department of Health and Human Services.
Identification
Copyright
© 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine.