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Letter to the Editor| Volume 21, ISSUE 10, P1511-1512.e1, October 2020

Factors Associated With Response to Repeated Cerebrospinal Fluid Removal Procedures in Nonsurgical Candidates With Idiopathic Normal Pressure Hydrocephalus

Published:July 14, 2020DOI:https://doi.org/10.1016/j.jamda.2020.05.057
Factors Associated With Response to Repeated Cerebrospinal Fluid Removal Procedures in Nonsurgical Candidates With Idiopathic Normal Pressure Hydrocephalus
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      Patients affected by idiopathic normal-pressure hydrocephalus (iNPH) are usually older and frail, and if left untreated, will inevitably undergo a significant decline in their functional status.
      • Andrén K.
      • Wikkelsø C.
      • Tisell M.
      • Hellström P.
      Natural course of idiopathic normal pressure hydrocephalus.
      J Neurol Neurosurg Psychiatry. 2014; 85: 806-810
      In a previous work, we explored the safety and effectiveness of repeated cerebrospinal fluid (CSF) removal procedures (CSF tap) for the management of iNPH symptoms in patients ineligible for surgical intervention. Treated patients tended to remain functionally and cognitively stable over an up to 42-month follow-up period compared with those who, for different reasons, did not follow the protocol.
      • Rossi P.D.
      • Damanti S.
      • Nani C.
      • et al.
      Repeated cerebrospinal fluid removal procedure in older patients with idiopathic normal pressure hydrocephalus ineligible for surgical treatment.
      J Am Med Dir Assoc. 2019; 20: 373-376.e3
      The present analyses are aimed at better quantifying the duration of the benefit after a CSF tap and exploring the role played by frailty.
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        View in Article
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      Article info

      Publication history

      Published online: July 14, 2020

      Identification

      DOI: https://doi.org/10.1016/j.jamda.2020.05.057

      Copyright

      © 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine.

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