Patients affected by idiopathic normal-pressure hydrocephalus (iNPH) are usually older and frail, and if left untreated, will inevitably undergo a significant decline in their functional status.
1In a previous work, we explored the safety and effectiveness of repeated cerebrospinal fluid (CSF) removal procedures (CSF tap) for the management of iNPH symptoms in patients ineligible for surgical intervention. Treated patients tended to remain functionally and cognitively stable over an up to 42-month follow-up period compared with those who, for different reasons, did not follow the protocol.
- Andrén K.
- Wikkelsø C.
- Tisell M.
- Hellström P.
Natural course of idiopathic normal pressure hydrocephalus.
J Neurol Neurosurg Psychiatry. 2014; 85: 806-810
2The present analyses are aimed at better quantifying the duration of the benefit after a CSF tap and exploring the role played by frailty.
- Rossi P.D.
- Damanti S.
- Nani C.
- et al.
Repeated cerebrospinal fluid removal procedure in older patients with idiopathic normal pressure hydrocephalus ineligible for surgical treatment.
J Am Med Dir Assoc. 2019; 20: 373-376.e3
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- Natural course of idiopathic normal pressure hydrocephalus.J Neurol Neurosurg Psychiatry. 2014; 85: 806-810
- Repeated cerebrospinal fluid removal procedure in older patients with idiopathic normal pressure hydrocephalus ineligible for surgical treatment.J Am Med Dir Assoc. 2019; 20: 373-376.e3
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Published online: July 14, 2020
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