Abstract
Objectives
Design
Setting and Participants
Methods
Results
Conclusions and Implications
Keywords
Improving Medicare Post Acute Care Transformation Act. IMPACT Act of 2014 2014:113–185.
Bundled Payments for Care Improvement (BPCI) initiative: General information.
Comprehensive Care for Joint Replacement model.
Improving Medicare Post Acute Care Transformation Act. IMPACT Act of 2014 2014:113–185.
Discharge to community claims-based measure for home health: Risk adjustment methodology. 2016.
Discharge to community measure. 2014.
Methods
Data Sources
Patient Cohort

Outcome
Primary Predictors
Pain assessment and management standards for hospitals.
- Heslin K.C.
- Elixhauser A.
- Steiner C.A.
Covariates
Analysis
Results
Cohort Characteristics
Hip | Knee | |
---|---|---|
n (%) | n (%) | |
Total | 79,725 (100) | 136,070 (100) |
Discharged to community | 66,013 (82.80) | 110,379 (81.13) |
Sex | ||
Female | 42,745 (53.62) | 81,858 (60.16) |
Male | 36,980 (46.38) | 54,212 (39.84) |
Age | ||
<55 | 14,334 (17.98) | 16,193 (11.90) |
55–64 | 25,046 (31.42) | 43,898 (32.26) |
65–74 | 24,462 (30.68) | 48,968 (35.99) |
75+ | 15,883 (19.92) | 27,011 (19.85) |
Region | ||
Midwest | 38,536 (48.34) | 67,739 (49.78) |
Northeast | 7150 (8.97) | 7980 (5.86) |
Other | 1204 (1.51) | 1869 (1.37) |
South | 22,114 (27.74) | 42,724 (31.40) |
West | 10,721 (13.45) | 15,758 (11.58) |
Race | ||
African American | 5718 (7.17) | 9924 (7.29) |
Asian | 261 (0.33) | 710 (0.52) |
White | 71,072 (89.15) | 120,008 (88.20) |
Other | 2674 (3.35) | 5428 (3.99) |
Ethnicity | ||
Hispanic | 1529 (1.92) | 3428 (2.52) |
Not Hispanic | 74,724 (93.73) | 127,334 (93.58) |
Unknown | 3472 (4.35) | 5308 (3.90) |
Insurance | ||
Medicare only | 26,057 (32.68) | 46,314 (34.04) |
Medicaid only | 2643 (3.32) | 3303 (2.43) |
Supplemental insurance (2 or more) | 11,939 (14.98) | 24,314 (17.87) |
Commercial/Other (1 insurance) | 35,716 (44.80) | 56,769 (41.72) |
Unknown | 3370 (4.23) | 5370 (3.95) |
Pain | ||
0 | 8573 (10.75) | 11,150 (8.19) |
1–3 | 41,823 (52.46) | 63,760 (46.86) |
4–6 | 25,165 (31.56) | 52,743 (38.76) |
7–10 | 4164 (5.22) | 8417 (6.19) |
Body mass index | ||
Underweight (<18.5) | 661 (0.83) | 276 (0.20) |
Normal (18.5–24.9) | 15,295 (19.18) | 12,485 (9.18) |
Overweight (25.0–29.9) | 26,581 (33.34) | 36,546 (26.86) |
Obese (≥30.0) | 37,188 (46.65) | 86,763 (63.76) |
Smoking status | ||
Current smoker | 12,440 (15.60) | 15,758 (11.58) |
Never smoked | 29,101 (36.50) | 52,120 (38.30) |
Not currently smoking | 38,028 (47.70) | 67,911 (49.91) |
Other | 156 (0.20) | 281 (0.21) |
Alcohol consumption | ||
Consumes alcohol | 48,423 (60.74) | 75,736 (55.66) |
Does not consume alcohol | 28,452 (35.69) | 56,114 (41.24) |
8 or more drinks/week | 2081 (2.61) | 2914 (2.14) |
Other | 769 (0.96) | 1306 (0.96) |
Substance use disorder | ||
No | 75,959 (95.28) | 131,887 (96.93) |
Yes | 3766 (4.72) | 4183 (3.07) |
Year | ||
2011 | 2070 (2.60) | 4211 (3.09) |
2012 | 6807 (8.54) | 13,040 (9.58) |
2013 | 10,532 (13.21) | 19,368 (14.23) |
2014 | 12,330 (15.47) | 21,790 (16.01) |
2015 | 14,469 (18.15) | 24,349 (17.89) |
2016 | 16,215 (20.34) | 26,298 (19.33) |
2017 | 15,134 (18.98) | 24,052 (17.68) |
2018 | 2168 (2.72) | 2962 (2.18) |
Community Discharge
Effect | Community Discharge, % | Model 1 | Model 2 |
---|---|---|---|
OR (95% CI) | OR (95% CI) | ||
Sex | |||
Male | 78.60 | REF | REF |
Female | 87.66 | 0.60 (0.57–0.62) | 0.63 (0.60–0.66) |
Age category | |||
<55 | 94.13 | REF | REF |
55–64 | 91.52 | 0.60 (0.55–0.66) | 0.55 (0.50–0.60) |
65–74 | 82.87 | 0.41 (0.37–0.45) | 0.32 (0.30–0.36) |
75+ | 58.73 | 0.12 (0.11–0.14) | 0.09 (0.09–0.10) |
Region | |||
West | 85.44 | REF | REF |
Midwest | 82.08 | 0.76 (0.71–0.81) | 0.73 (0.68–0.78) |
Northeast | 84.27 | 0.68 (0.62–0.74) | 0.65 (0.59–0.71) |
Other | 79.73 | 0.56 (0.48–0.67) | 0.59 (0.50–0.69) |
South | 82.46 | 0.82 (0.77–0.89) | 0.89 (0.83–0.96) |
Race | |||
White | 83.08 | REF | REF |
African American | 77.60 | 0.48 (0.45–0.52) | 0.56 (0.52–0.60) |
Asian | 86.97 | 1.08 (0.73–1.59) | 1.03 (0.69–1.54) |
Other | 86.20 | 0.94 (0.82–1.07) | 0.97 (0.85–1.11) |
Ethnicity | |||
Hispanic | 85.35 | REF | REF |
Not Hispanic | 82.60 | 1.14 (0.97–1.34) | 1.11 (0.94–1.32) |
Unknown | 85.94 | 1.16 (0.96–1.40) | 1.18 (0.98–1.43) |
Insurance | |||
Medicare only | 72.73 | REF | REF |
Commercial/Other (1 insurance) | 93.10 | 2.16 (2.03–2.31) | 1.95 (1.82–2.08) |
Medicaid only | 83.81 | 0.68 (0.60–0.77) | 0.85 (0.75–0.96) |
Supplemental insurance (2 or more) | 73.52 | 0.90 (0.85–0.95) | 0.93 (0.88–0.98) |
Unknown | 83.62 | 1.34 (1.21–1.49) | 1.30 (1.17–1.44) |
Year | |||
2011 | 77.78 | REF | REF |
2012 | 77.29 | 1.00 (0.88–1.14) | 0.95 (0.83–1.08) |
2013 | 79.01 | 1.09 (0.96–1.23) | 1.04 (0.92–1.18) |
2014 | 81.12 | 1.24 (1.09–1.40) | 1.18 (1.04–1.33) |
2015 | 82.18 | 1.35 (1.19–1.52) | 1.27 (1.12–1.44) |
2016 | 85.28 | 1.80 (1.59–2.04) | 1.72 (1.52–1.96) |
2017 | 87.07 | 2.17 (1.91–2.46) | 2.05 (1.80–2.33) |
2018 | 88.75 | 2.63 (2.19–3.16) | 2.43 (2.02–2.93) |
Pain | |||
0 | 80.91 | REF | |
1–3 | 85.54 | 1.06 (0.99–1.14) | |
4–6 | 80.55 | 0.62 (0.58–0.67) | |
7–10 | 72.81 | 0.40 (0.36–0.44) | |
Body mass index | |||
Normal (18.5–24.9) | 80.30 | REF | |
Underweight (<18.5) | 72.47 | 0.75 (0.62–0.92) | |
Overweight (25.0–29.9) | 84.34 | 1.12 (1.06–1.19) | |
Obese (≥30.0) | 82.91 | 0.81 (0.76–0.85) | |
Smoking status | |||
Never smoked | 84.37 | ||
Current smoker | 85.39 | 0.82 (0.77–0.88) | |
Not currently smoking | 80.79 | 0.85 (0.81–0.89) | |
Other | 72.44 | 0.70 (0.47–1.06) | |
Alcohol consumption | |||
Does not consume alcohol | 75.42 | ||
Consumes alcohol | 87.02 | 1.64 (1.57–1.71) | |
8 or more drinks/week | 87.22 | 1.70 (1.48–1.96) | |
Other | 78.54 | 1.16 (0.96–1.41) | |
Substance use disorder | |||
No | 83.00 | ||
Yes | 78.86 | 0.55 (0.50–0.60) |
Effect | Community Discharge, % | Model 1 | Model 2 |
---|---|---|---|
OR (95% CI) | OR (95% CI) | ||
Sex | |||
Male | 77.95 | REF | REF |
Female | 85.94 | 0.59 (0.58–0.61) | 0.62 (0.60–0.64) |
Age category | |||
<55 | 91.72 | REF | REF |
55–64 | 89.02 | 0.66 (0.62–0.70) | 0.63 (0.59–0.67) |
65–74 | 80.47 | 0.46 (0.43–0.50) | 0.40 (0.37–0.43) |
75+ | 63.17 | 0.20 (0.18–0.21) | 0.16 (0.15–0.17) |
Region | |||
West | 85.25 | REF | REF |
Midwest | 80.79 | 0.69 (0.65–0.73) | 0.69 (0.66–0.73) |
Northeast | 79.39 | 0.53 (0.50–0.58) | 0.53 (0.50–0.58) |
Other | 79.24 | 0.60 (0.53–0.68) | 0.61 (0.54–0.70) |
South | 80.57 | 0.74 (0.70–0.78) | 0.80 (0.75–0.84) |
Race | |||
White | 81.50 | REF | REF |
African American | 75.29 | 0.56 (0.53–0.59) | 0.62 (0.59–0.65) |
Asian | 76.48 | 0.74 (0.62–0.89) | 0.70 (0.58–0.85) |
Other | 84.29 | 1.05 (0.96–1.15) | 1.09 (1.00–1.19) |
Ethnicity | |||
Hispanic | 82.53 | REF | REF |
Not Hispanic | 81.01 | 1.14 (1.03–1.27) | 1.08 (0.98–1.20) |
Unknown | 83.20 | 1.08 (0.95–1.22) | 1.04 (0.92–1.18) |
Insurance | |||
Medicare only | 73.47 | REF | REF |
Commercial/Other (1 insurance) | 90.17 | 1.86 (1.78–1.95) | 1.73 (1.66–1.82) |
Medicaid only | 83.32 | 0.91 (0.82–1.01) | 1.04 (0.93–1.15) |
Supplemental insurance (2 or more) | 74.06 | 0.93 (0.90–0.97) | 0.95 (0.91–0.99) |
Unknown | 82.42 | 1.41 (1.31–1.53) | 1.40 (1.29–1.51) |
Year | |||
2011 | 74.42 | REF | REF |
2012 | 75.54 | 1.12 (1.03–1.22) | 1.07 (0.98–1.16) |
2013 | 76.93 | 1.20 (1.11–1.31) | 1.15 (1.06–1.25) |
2014 | 79.50 | 1.39 (1.28–1.51) | 1.33 (1.22–1.44) |
2015 | 81.07 | 1.58 (1.45–1.71) | 1.50 (1.38–1.62) |
2016 | 84.20 | 2.07 (1.91–2.25) | 1.95 (1.79–2.12) |
2017 | 86.15 | 2.49 (2.29–2.70) | 2.36 (2.16–2.57) |
2018 | 87.27 | 2.81 (2.46–3.22) | 2.65 (2.31–3.03) |
Pain | |||
0 | 77.57 | REF | |
1–3 | 82.62 | 1.13 (1.07–1.19) | |
4–6 | 81.01 | 0.87 (0.82–0.92) | |
7–10 | 75.32 | 0.60 (0.56–0.64) | |
Body mass index | |||
Normal (18.5–24.9) | 79.58 | REF | |
Underweight (<18.5) | 78.26 | 1.03 (0.75–1.40) | |
Overweight (25.0–29.9) | 82.29 | 1.01 (0.96–1.07) | |
Obese (≥30.0) | 80.88 | 0.73 (0.69–0.77) | |
Smoking status | |||
Never smoked | 82.72 | REF | |
Current smoker | 84.52 | 0.90 (0.85–0.95) | |
Not currently smoking | 79.17 | 0.82 (0.79–0.84) | |
Other | 71.53 | 0.60 (0.45–0.80) | |
Alcohol consumption | |||
Does not consume alcohol | 75.79 | REF | |
Consumes alcohol | 84.83 | 1.47 (1.42–1.51) | |
8 or more drinks/week | 88.13 | 1.85 (1.64–2.09) | |
Other | 80.32 | 1.41 (1.22–1.63) | |
Substance use disorder | |||
No | 81.29 | REF | |
Yes | 76.21 | 0.57 (0.53–0.62) |
Discussion
Discharge to community claims-based measure for home health: Risk adjustment methodology. 2016.
Discharge to community measure. 2014.
- Dummit L.
- Smathers K.
- Bright O.J.
- et al.
- Dummit L.
- Smathers K.
- Bright O.J.
- et al.
- Dummit L.
- Smathers K.
- Bright O.J.
- et al.
Limitations
Conclusions and Implications
Acknowledgments
Appendix
ICD-9 | ICD-10 | CPT |
---|---|---|
81.51 | 0SR90J9, Replacement of Right Hip Joint with Synthetic Substitute, Cemented, Open Approach 0SR90JA, Replacement of Right Hip Joint with Synthetic Substitute, Uncemented, Open Approach 0SR90JZ, Replacement of Right Hip Joint with Synthetic Substitute, Open Approach 0SRB0J9, Replacement of Left Hip Joint with Synthetic Substitute, Cemented, Open Approach 0SRB0JA, Replacement of Left Hip Joint with Synthetic Substitute, Uncemented, Open Approach 0SRB0JZ, Replacement of Left Hip Joint with Synthetic Substitute, Open Approach | 27130, Arthroplasty, acetabular and proximal femoral prosthetic replacement (total hip arthroplasty), with or without autograft or allograft |
81.54 | 0SRC07Z, Replacement of Right Knee Joint with Autologous Tissue Substitute, Open Approach 0SRC0JZ, Replacement of Right Knee Joint with Synthetic Substitute, Open Approach 0SRC0KZ, Replacement of Right Knee Joint with Nonautologous Tissue Substitute, Open Approach 0SRC0LZ, Replacement of Right Knee Joint with Medial Unicondylar Synthetic Substitute, Open Approach 0SRD07Z, Replacement of Left Knee Joint with Autologous Tissue Substitute, Open Approach 0SRD0JZ, Replacement of Left Knee Joint with Synthetic Substitute, Open Approach 0SRD0KZ, Replacement of Left Knee Joint with Nonautologous Tissue Substitute, Open Approach 0SRD0LZ, Replacement of Left Knee Joint with Medial Unicondylar Synthetic Substitute, Open Approach 0SRT07Z, Replacement of Right Knee Joint, Femoral Surface with Autologous Tissue Substitute, Open Approach 0SRT0JZ, Replacement of Right Knee Joint, Femoral Surface with Synthetic Substitute, Open Approach 0SRT0KZ, Replacement of Right Knee Joint, Femoral Surface with Nonautologous Tissue Substitute, Open Approach 0SRU07Z, Replacement of Left Knee Joint, Femoral Surface with Autologous Tissue Substitute, Open Approach 0SRU0JZ, Replacement of Left Knee Joint, Femoral Surface with Synthetic Substitute, Open Approach 0SRU0KZ, Replacement of Left Knee Joint, Femoral Surface with Nonautologous Tissue Substitute, Open Approach 0SRV07Z, Replacement of Right Knee Joint, Tibial Surface with Autologous Tissue Substitute, Open Approach 0SRV0JZ, Replacement of Right Knee Joint, Tibial Surface with Synthetic Substitute, Open Approach 0SRV0KZ, Replacement of Right Knee Joint, Tibial Surface with Nonautologous Tissue Substitute, Open Approach 0SRW07Z, Replacement of Left Knee Joint, Tibial Surface with Autologous Tissue Substitute, Open Approach 0SRW0JZ, Replacement of Left Knee Joint, Tibial Surface with Synthetic Substitute, Open Approach 0SRW0KZ, Replacement of Left Knee Joint, Tibial Surface with Nonautologous Tissue Substitute, Open Approach | 27447, Arthroplasty, knee, condyle and plateau; medial AND lateral compartments with or without patella resurfacing (total knee arthroplasty) |
Effect | Community Discharge % | Model 1 | Model 2 |
---|---|---|---|
OR (95% CI) | OR (95% CI) | ||
Sex | |||
Male | 88.7 | REF | REF |
Female | 80.1 | 0.59 (0.56–0.62) | 0.62 (0.59–0.66) |
Age category | |||
<55 | 94.5 | REF | REF |
55–64 | 92.2 | 0.61 (0.55–0.67) | 0.55 (0.50–0.61) |
65–74 | 83.9 | 0.41 (0.37–0.46) | 0.32 (0.28–0.35) |
75+ | 60.3 | 0.12 (0.11–0.14) | 0.09 (0.08–0.10) |
Region | |||
West | 87.5 | REF | REF |
Midwest | 83.0 | 0.69 (0.64–0.75) | 0.67 (0.62–0.73) |
Northeast | 85.6 | 0.65 (0.58–0.72) | 0.63 (0.57–0.71) |
Other | 80.1 | 0.51 (0.42–0.62) | 0.51 (0.42–0.62) |
South | 84.1 | 0.85 (0.77–0.93) | 0.87 (0.79–0.96) |
Race | |||
Caucasian | 84.3 | REF | REF |
African American | 78.7 | 0.47 (0.43–0.52) | 0.56 (0.51–0.61) |
Asian | 89.4 | 1.18 (0.74–1.89) | 1.16 (0.71–1.87) |
Other | 87.5 | 0.93 (0.80–1.09) | 0.99 (0.85–1.16) |
Ethnicity | |||
Hispanic | 86.8 | REF | REF |
Not Hispanic | 83.9 | 1.09 (0.90–1.32) | 1.06 (0.87–1.29) |
Unknown | 87.2 | 1.10 (0.88–1.37) | 1.12 (0.90–1.40) |
Insurance | |||
Medicare only | 74.1 | REF | REF |
Commercial/Other (1 insurance) | 85.4 | 2.19 (2.02–2.37) | 1.97 (1.82–2.13) |
Medicaid only | 84.4 | 0.66 (0.57–0.76) | 0.81 (0.70–0.94) |
Supplemental insurance (2 or more) | 75.1 | 0.89 (0.83–0.95) | 0.92 (0.86–0.98) |
Unknown | 93.7 | 1.43 (1.26–1.62) | 1.37 (1.21–1.56) |
Year | |||
2011 | 58.7 | REF | REF |
2012 | 78.3 | 2.26 (1.46–3.49) | 2.23 (1.44–3.46) |
2013 | 80.2 | 2.51 (1.63–3.88) | 2.53 (1.64–3.92) |
2014 | 82.6 | 2.90 (1.88–4.46) | 2.90 (1.88–4.49) |
2015 | 83.8 | 3.21 (2.08–4.95) | 3.20 (2.07–4.95) |
2016 | 86.1 | 4.11 (2.67–6.33) | 4.18 (2.70–6.46) |
2017 | 88.1 | 5.12 (3.32–7.89) | 5.15 (3.33–7.98) |
2018 | 89.8 | 6.49 (4.10–10.27) | 6.48 (4.08–10.31) |
Pain | |||
0 | 82.4 | REF | |
1–3 | 86.6 | 1.00 (0.92–1.08) | |
4–6 | 81.5 | 0.56 (0.51–0.61) | |
7–10 | 72.8 | 0.34 (0.30–0.38) | |
Body mass index | |||
Normal (18.5–24.9) | 76.1 | REF | |
Underweight (<18.5) | 82.6 | 0.75 (0.59–0.97) | |
Overweight (25.0–29.9) | 85.6 | 1.08 (1.00–1.16) | |
Obese (≥30.0) | 83.7 | 0.74 (0.69–0.79) | |
Smoking status | |||
Never smoked | 85.4 | REF | |
Current smoker | 86.7 | 0.84 (0.77–0.91) | |
Not currently smoking | 82.1 | 0.84 (0.80–0.89) | |
Other | 77.8 | 0.81 (0.35–1.86) | |
Alcohol consumption | |||
Does not consume alcohol | 76.9 | REF | |
Consumes alcohol | 87.8 | 1.65 (1.56–1.73) | |
8 or more drinks/week | 88.7 | 1.88 (1.59–2.22) | |
Other | 80.1 | 1.24 (1.01–1.53) | |
Substance use disorder | |||
No | 84.2 | REF | |
Yes | 81.8 | 0.61 (0.54–0.68) |
Effect | Community Discharge, % | Model 1 | Model 2 |
---|---|---|---|
OR (95% CI) | OR (95% CI) | ||
Sex | |||
Male | 86.4 | REF | REF |
Female | 78.5 | 0.59 (0.57–0.61) | 0.62 (0.60–0.64) |
Age category | |||
<55 | 91.7 | REF | REF |
55–64 | 89.2 | 0.67 (0.62–0.72) | 0.63 (0.58–0.68) |
65–74 | 80.9 | 0.49 (0.46–0.53) | 0.42 (0.39–0.45) |
75+ | 63.9 | 0.21 (0.19–0.23) | 0.17 (0.15–0.18) |
Region | |||
West | 86.7 | REF | REF |
Midwest | 81.4 | 0.66 (0.62–0.71) | 0.67 (0.62–0.71) |
Northeast | 80.0 | 0.52 (0.48–0.57) | 0.52 (0.48–0.57) |
Other | 79.4 | 0.57 (0.50–0.66) | 0.59 (0.51–0.68) |
South | 80.6 | 0.70 (0.66–0.75) | 0.75 (0.70–0.80) |
Race | |||
Caucasian | 82.1 | REF | REF |
African American | 75.0 | 0.54 (0.51–0.58) | 0.61 (0.57–0.65) |
Asian | 77.4 | 0.74 (0.60–0.91) | 0.71 (0.57–0.87) |
Other | 84.9 | 1.08 (0.98–1.19) | 1.12 (1.02–1.24) |
Ethnicity | |||
Hispanic | 82.7 | REF | REF |
Not Hispanic | 81.6 | 1.17 (1.04–1.31) | 1.08 (0.96–1.22) |
Unknown | 83.6 | 1.04 (0.91–1.20) | 1.00 (0.87–1.15) |
Insurance | |||
Medicare only | 73.8 | REF | REF |
Commercial/Other (1 insurance) | 85.2 | 1.95 (1.85–2.06) | 1.80 (1.71–1.90) |
Medicaid only | 83.9 | 0.96 (0.85–1.08) | 1.09 (0.97–1.23) |
Supplemental insurance (2 or more) | 74.6 | 0.95 (0.91–1.00) | 0.98 (0.94–1.03) |
Unknown | 90.4 | 1.66 (1.51–1.83) | 1.64 (1.48–1.80) |
Year | |||
2011 | 44.6 | REF | REF |
2012 | 76.2 | 5.12 (4.00–6.55) | 5.27 (4.10–6.76) |
2013 | 77.2 | 5.47 (4.28–7.00) | 5.67 (4.43–7.27) |
2014 | 80.1 | 6.43 (5.03–8.22) | 6.68 (5.22–8.57) |
2015 | 81.7 | 7.40 (5.79–9.45) | 7.65 (5.97–9.81) |
2016 | 84.8 | 9.55 (7.47–12.21) | 9.86 (7.69–12.64) |
2017 | 86.3 | 11.09 (8.66–14.19) | 11.50 (8.96–14.75) |
2018 | 87.2 | 12.20 (9.28–16.05) | 12.70 (9.63–16.74) |
Pain | |||
0 | 77.0 | REF | |
1–3 | 83.2 | 1.16 (1.09–1.25) | |
4–6 | 81.4 | 0.88 (0.82–0.94) | |
7–10 | 75.3 | 0.57 (0.52–0.63) | |
Body mass index | |||
Normal (18.5–24.9) | 81.1 | REF | |
Underweight (<18.5) | 80.6 | 1.24 (0.85–1.80) | |
Overweight (25.0–29.9) | 83.0 | 1.01 (0.94–1.08) | |
Obese (≥30.0) | 81.3 | 0.71 (0.67–0.76) | |
Smoking status | |||
Never smoked | 83.2 | REF | |
Current smoker | 85.2 | 0.92 (0.86–0.98) | |
Not currently smoking | 79.6 | 0.80 (0.77–0.83) | |
Other | 73.5 | 0.68 (0.39–1.16) | |
Alcohol consumption | |||
Does not consume alcohol | 76.0 | REF | |
Consumes alcohol | 85.2 | 1.50 (1.45–1.56) | |
8 or more drinks/week | 89.2 | 2.17 (1.89–2.49) | |
Other | 80.0 | 1.38 (1.18–1.60) | |
Substance use disorder | |||
No | 81.8 | REF | |
Yes | 77.4 | 0.59 (0.54–0.65) |
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Footnotes
This study was supported with funding from the National Institutes of Health (R01-AG033134; P2C HD065702; R01-HD069443; P30-AG024832, K12 HD055929, 1UL1TR001439; T32HS026133–02). The authors did receive grants from National Institute on Aging, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Center for Advancing Translational Sciences, and Agency for Healthcare Research and Quality, during the conduct of the study. The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
The authors declare no conflicts of interest.
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