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Original Study| Volume 22, ISSUE 1, P90-95, January 2021

Electronic Medication Management System Introduction and Deprescribing Practice in Post-Acute Care

  • Susanto Winata
    Affiliations
    Department of Rehabilitation and Aged Care, Caulfield Hospital, The Alfred, Melbourne, Victoria, Australia

    Department of Medicine, Peninsula Health, Melbourne, Victoria, Australia
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  • Michelle Liacos
    Affiliations
    Pharmacy Department, The Alfred, Melbourne, Victoria, Australia
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  • Amelia Crabtree
    Affiliations
    Department of Rehabilitation and Aged Care, Caulfield Hospital, The Alfred, Melbourne, Victoria, Australia
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  • Amy Page
    Affiliations
    Pharmacy Department, The Alfred, Melbourne, Victoria, Australia

    Centre for Medicine Use and Safety, Monash University, Parkville, Victoria, Australia
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  • Chris Moran
    Correspondence
    Address correspondence to Chris Moran, PhD, Academic Unit, Peninsula Health, Peninsula Clinical School, Central Clinical School, Monash University, PO Box 52, Frankston, VIC 3199, Australia.
    Affiliations
    Department of Rehabilitation and Aged Care, Caulfield Hospital, The Alfred, Melbourne, Victoria, Australia

    Academic Unit, Peninsula Clinical School, Central Clinical School, Monash University, Melbourne, Victoria, Australia

    Department of Geriatric Medicine, Peninsula Health, Melbourne, Victoria, Australia
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Published:November 21, 2020DOI:https://doi.org/10.1016/j.jamda.2020.10.015

      Abstract

      Objective

      To determine the effect of introducing an electronic medication management system (EMMS) on deprescribing practice in a post-acute hospital setting.

      Design

      This study used a before-after study design.

      Setting and Participants

      This study examined the admission and discharge medications prescribed to patients admitted to an Australian post-acute hospital before and after the introduction of an EMMS.

      Methods

      Data were collected over a 1-month period before and after the introduction of an EMMS and included summary measures of drug burden including Potentially Inappropriate Medications and the Drug Burden Index. We calculated and compared admission and discharge medication prescription as well as change in medication use before and after the introduction of an EMMS.

      Results

      Medication prescription data were available for 121 people before and 107 people after EMMS introduction. In both phases, when compared with admission, those discharged were prescribed fewer medications (mean reduction pre-EMMS = 2.9, P < .001, post-EMMS = 2.6, P < .001), fewer Potentially Inappropriate Medications (mean reduction pre-EMMS = 0.4, P < .001, post-EMMS = 0.6, P < .001) and had lower Drug Burden Index (mean reduction pre-EMMS = 0.1, P < .001, post-EMMS = 0.2, P < .001). The degree of reduction in each measure was similar before and after EMMS introduction.

      Conclusions and Implications

      The introduction of an EMMS did not affect deprescribing practice in a post-acute hospital setting. Future work is required to explore the potential for clinical decision support within an EMMS to further improve the safety and effectiveness of deprescribing within post-acute care.

      Keywords

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      References

        • Beer C.
        • Hyde Z.
        • Almeida O.P.
        • et al.
        Quality use of medicines and health outcomes among a cohort of community dwelling older men: An observational study.
        Br J Clin Pharmacol. 2011; 71: 592-599
        • Page A.T.
        • Potter K.
        • Clifford R.
        • Etherton-Beer C.
        Deprescribing in older people.
        Maturitas. 2016; 91: 115-134
        • Elliott R.A.
        • Booth J.C.
        Problems with medicine use in older Australians: A review of recent literature.
        J Pharm Pract Res. 2014; 44: 258-271
        • Hubbard R.E.
        • Peel N.M.
        • Scott I.A.
        • et al.
        Polypharmacy among inpatients aged 70 years or older in Australia.
        Med J Aust. 2015; 202: 373-377
        • Page A.
        • Clifford R.
        • Potter K.
        • Etherton-Beer C.
        A concept analysis of deprescribing medications in older people.
        J Pharm Pract Res. 2018; 48: 132-148
        • Page A.T.
        • Clifford R.M.
        • Potter K.
        • et al.
        The feasibility and effect of deprescribing in older adults on mortality and health: A systematic review and meta-analysis.
        Br J Clin Pharmacol. 2016; 82: 583-623
        • Thillainadesan J.
        • Gnjidic D.
        • Green S.
        • Hilmer S.N.
        Impact of deprescribing interventions in older hospitalised patients on prescribing and clinical outcomes: A systematic review of randomised trials.
        Drugs Aging. 2018; 35: 303-319
        • Esmaeil Z.P.
        • Tremblay M.C.
        A review of the literature and proposed classification on e-prescribing: Functions, assimilation stages, benefits, concerns, and risks.
        Res Social Adm Pharm. 2016; 12: 1-19
        • Delpierre C.
        • Cuzin L.
        • Fillaux J.
        • et al.
        A systematic review of computer-based patient record systems and quality of care: More randomized clinical trials or a broader approach?.
        Int J Qual Health Care. 2004; 16: 407-416
        • Mitchell E.
        • Sullivan F.
        A descriptive feast but an evaluative famine: Systematic review of published articles on primary care computing during 1980–97.
        BMJ. 2001; 322: 279-282
        • Wang C.J.
        • Patel M.H.
        • Schueth A.J.
        • et al.
        Perceptions of standards-based electronic prescribing systems as implemented in outpatient primary care: A physician survey.
        J Am Med Inform Assoc. 2009; 16: 493-502
        • Smith H.
        • Miller K.
        • Barnett N.
        • et al.
        Person-centred care including deprescribing for older people.
        Pharmacy. 2019; 7: 101
        • Schmader K.E.
        • Hanlon J.T.
        • Pieper C.F.
        • et al.
        Effects of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderly.
        Am J Med. 2004; 116: 394-401
        • Hellstrom L.
        • Waern K.
        • Montelius E.
        • et al.
        Physicians' attitudes towards ePrescribing-evaluation of a Swedish full-scale implementation.
        BMC Medical Inform Decis Mak. 2009; 9: 37
        • Pizzi L.T.
        • Suh D.-C.
        • Barone J.
        • Nash D.B.
        Factors related to physicians' adoption of electronic prescribing: Results from a national survey.
        Am J Med Qual. 2005; 20: 22-32
        • Charlson M.E.
        • Pompei P.
        • Ales K.L.
        • MacKenzie C.R.
        A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation.
        J Chron Dis. 1987; 40: 373-383
        • Pugh R.
        • Murray-Lyon I.
        • Dawson J.
        • et al.
        Transection of the oesophagus for bleeding oesophageal varices.
        Br J Surg. 1973; 60: 646-649
        • Molloy D.W.
        • Standish T.I.
        A guide to the standardized Mini-Mental State Examination.
        Int Psychogeriatr. 1997; 9: 87-94
        • Storey J.E.
        • Rowland J.T.
        • Conforti D.A.
        • Dickson H.G.
        The Rowland universal dementia assessment scale (RUDAS): A multicultural cognitive assessment scale.
        Int Psychogeriatr. 2004; 16: 13-31
        • O'Mahony D.
        • O'Sullivan D.
        • Byrne S.
        • et al.
        STOPP/START criteria for potentially inappropriate prescribing in older people: Version 2.
        Age Ageing. 2015; 44: 213-218
        • Curtain C.M.
        • Bindoff I.K.
        • Westbury J.L.
        • et al.
        A comparison of prescribing criteria when applied to older community-based Patients.
        Drugs Aging. 2013; 30: 935-943
        • Hilmer S.N.
        • Mager D.E.
        • Simonsick E.M.
        • et al.
        A Drug Burden Index to define the functional burden of medications in older people.
        Arch Intern Med. 2007; 167: 781-787
        • MIMS Australia Pty Ltd
        MIMSOnline.
        (Available at:)
        • Hilmer S.N.
        Calculating and using the Drug Burden Index score in research and practice.
        Expert Rev Clin Pharmacol. 2018; 11: 1053-1055
        • Kouladjian L.
        • Gnjidic D.
        • Chen T.
        • et al.
        The Drug Burden Index in older adults: Theoretical and practical issues.
        Clin Int Aging. 2014; 9: 1503-1515
        • Wouters H.
        • Van der Meer H.
        • Taxis K.
        Quantification of anticholinergic and sedative drug load with the Drug Burden Index: A review of outcomes and methodological quality of studies.
        Eur J Clin Pharmacol. 2017; 73: 257-266
        • Dalton K.
        • O'Brien G.
        • O'Mahony D.
        • Byrne S.
        Computerised interventions designed to reduce potentially inappropriate prescribing in hospitalised older adults: A systematic review and meta-analysis.
        Age Ageing. 2018; 47: 670-678
        • Desmedt S.
        • Spinewine A.
        • Jadoul M.
        • et al.
        Impact of a clinical decision support system for drug dosage in patients with renal failure.
        Int J Clin Pharm. 2018; 40: 1225-1233
        • Day R.O.
        • Roffe D.J.
        • Richardson K.L.
        • et al.
        Implementing electronic medication management at an Australian teaching hospital.
        Med J Aust. 2011; 195: 498-502
        • Kouladjian O'Donnell L.
        • Gnjidic D.
        • Chen T.F.
        • Hilmer S.N.
        Integration of an electronic Drug Burden Index risk assessment tool into Home Medicines Reviews: Deprescribing anticholinergic and sedative medications.
        Ther Adv Drug Saf. 2019; 10: 1-15
        • Best O.
        • Gnjidic D.
        • Hilmer S.N.
        • et al.
        Investigating polypharmacy and Drug Burden Index in hospitalised older people.
        Intern Med J. 2013; 43: 912-918
        • Brunetti E.
        • Aurucci M.L.
        • Boietti E.
        • et al.
        Clinical implications of potentially inappropriate prescribing according to STOPP/START version 2 criteria in older polymorbid patients discharged from geriatric and internal medicine wards: A prospective observational multicenter study.
        J Am Med Dir Assoc. 2019; 20: 1476
        • Cardwell K.
        • Hughes C.M.
        • Ryan C.
        The association between anticholinergic medication burden and health related outcomes in the ‘oldest old’: A systematic review of the literature.
        Drugs Aging. 2015; 32: 835-848