Abstract
Objectives
Along with deficit of attention, level of arousal is a primary criterion for the diagnosis
of delirium. The Observational Scale of Level of Arousal (OSLA) is a quick, simple,
and observational instrument used to evaluate the variation of arousal for rapid screening
of delirium in clinical practice. The current study aims to perform a cross-cultural
adaption of and to validate the Italian version of the OSLA scale to detect delirium
in older aged, hospitalized patients.
Design
Longitudinal study.
Setting and Participants
In hospital and transitional care setting. Old age patients.
Methods
A cross-cultural adaptation of the OSLA from English into Italian was conducted, including
back-translation. The validation of the OSLA was assessed in 116 older patients (age
>65 years) admitted to geriatric, internal medicine, and transitional care wards.
The 4 “A”s Test serves as the gold standard for the measurement of delirium.
Results
Incident delirium was assessed longitudinally at different time points during hospitalization.
The Italian version of OSLA demonstrated adequate internal consistency, specificity,
sensitivity, agreement, test-retest reliability, and sensitivity to change, indicating
adequate its clinometric properties in the detection of delirium in a real world hospitalized
cohort of older adults.
Conclusions and Implications
The current study is among the few studies to assess arousal as a core feature of
delirium by virtue of a longitudinal assessment of delirium, moving a step forward
in the implementation of a brief and easy to use delirium-screening tool for the measurement
of important clinical outcomes in a frail, old aged hospitalized population.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of the American Medical Directors AssociationAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Delirium in elderly people.Lancet. 2014; 383: 911-922
- Occurrence and outcome of delirium in medical in patients: A systematic review.Age Ageing. 2006; 35: 350-356
- Is delirium the cognitive harbinger of frailty in older adults’ a review about the existing evidence.Front Med (Lausanne). 2017; 4: 188
- The association between cognitive impairment and functional outcome in hospitalized older patients: A systematic review and meta-analysis.Age Ageing. 2017; 46: 559-567
- Diagnostic and statistical manual of mental disorders (DSM-5TM).5th ed. American Psychiatric Publishing, Arlington, VA2013
- Arousal changes and delirium in acute medically ill male older patients with and without dementia. A prospective study during hospitalization.Aging mental Health. 2018; 2018: 1-8
- Risk factors and outcomes among delirium subtypes in adult ICUs: A systematic review.J Crit Care. 2020; 56: 257-264
- Delirium arousal subtypes and their relationship with 6-months functional status and cognition.Psychosomatics. 2019; 60: 27-36
- Exploring delrium’ heterogeneity: Association between arousal subtypes at initial presentation and 6-month mortality in older emergency departments patients.Am J Geriatr Psychiatry. 2017; 25: 233-242
- Delirium point prevalence studies in inpatient setting: A systematic review and meta-analysis.J Clin Nurs. 2020; 135: 109-120
- Delirium motor subtypes and prognosis in hospitalized geriatric patients: A prospective observational study.J Psychosom Res. 2019; 122: 24-28
- Delirium subtypes and associated characteristics in older patients with exacerbations of chronic conditions.Am J Geriatr Psychiatry. 2018; 26: 1204-1212
- The diagnosis of delirium superimposed on dementia. An emerging challenge.J Am Med Dir Assoc. 2017; 18: 12-18
- Delirium superimposed on dementia: Challenges and opportunities.Nurs Clin North Am. 2019; 54: 541-550
- Differentiation of delirium, dementia and delirium superimposed on dementia in the older person.Br J Nurs. 2018; 27: 363-367
- Abnormal level of arousal as a predictor of delirium and inattention: An exploratory study.Am J Geriatr Psychiatry. 2013; 21: 1244-1253
- The Richmond Agitation Sedation Scale: validity and reliability in adult intensive care unit patients.Am J Respir Crit Care Med. 2002; 166: 1338-1344
- Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalized older people.Age Ageing. 2014; 43: 496‒502
- The 4 ‘A’s test for detecting delirium in acute medical patients: A diagnostic accuracy study.Health Technol assess. 2019; 23: 1-194
- A new data-based motor subtype schema for delirium.J Neuropsychiatry Clin Neurosci. 2008; 20: 185-193
- Cumulative illness rating scale.J Am Geriatr Soc. 1968; 16: 622-626
- Screening for undernutrition in geriatric practice: Developing the short-form mini-nutritional assessment (MNA-SF).J Gerontol A Biol Sci Med Sci. 2001; 56: M366-M372
- Functional evaluation: The Barthel Index.Md State Med J. 1965; 14: 61-65
- Assessment of older people: Self-maintaining and instrumental activities of daily living.Gerontologist. 1969; 9: 179-186
- The AD8: A brief informant interview to detect dementia.Neurology. 2005; 65: 559-564
- Validity of a verbally administered numeric rating scale to measure cancer pain intensity.Cancer Nurs. 1997; 20: 88-93
- Algoplus® Scale in older patients with dementia: A reliable real-world pain assessment tool.J Alzheimers Dis. 2017; 56: 519-527
- National Early Warning Score (NEWS): Standardizing the assessment of acute-illness severity in the NHS. Report of a working party.RCP, London2012
- The FNIH sarcopenia project: Rationale, study description, conference recommendations, and final estimates.J Gerontol A Biol Sci Med Sci. 2014; 69: 547-558
- Anticholinergic Cognitive Burden Scale. 2012 Update.(Available at:)http://www.acbcalc.comDate accessed: December 18, 2020
- Age-related deficit accumulation and the risk of late-life dementia.Alzheimers Res Ther. 2014; 6: 54-60
- Attention, arousal and other rapid bedside screening instruments for delirium in older patients: A systematic review of test accuracy studies.Age Ageing. 2018; 47: 644-653
Article info
Publication history
Published online: November 30, 2020
Footnotes
Lucia Martella and Luca Carmisciano contributed equally to this work.
The authors declare no conflicts of interest.
Identification
Copyright
© 2020 AMDA - The Society for Post-Acute and Long-Term Care Medicine.