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Letter to the Editor| Volume 22, ISSUE 4, P883-884, April 2021

Measure What Matters Most in Sarcopenia: Regional vs. Appendicular Muscle Mass?

      Sarcopenia is an important public health problem as it relates to physical frailty, mobility limitation, and even premature death.
      • Reginster J.Y.
      • Cooper C.
      • Rizzoli R.
      • et al.
      Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia.
      Although the importance of age-related loss of muscle mass and function (ie, sarcopenia) has been known for decades, sarcopenia still does not have a universally agreed clinical definition and diagnostic criteria. Therefore, its reported prevalence ranges between 10% and 40% depending on the assessment techniques, diagnostic criteria, and characteristics of the populations.
      • Mayhew A.J.
      • Amog K.
      • Phillips S.
      • et al.
      The prevalence of sarcopenia in community-dwelling older adults, an exploration of differences between studies and within definitions: A systematic review and meta-analyses.
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