Editorial| Volume 22, ISSUE 4, P725-727, April 2021

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Muscle Function and Sarcopenia: Clinical Implications of Recent Research

  • Jürgen M. Bauer
    Address correspondence to Jürgen M. Bauer, MD, PhD, Center for Geriatric Medicine and Network Aging Research, Heidelberg University, Rohrbacher Strasse 149, 69128 Heidelberg, Germany.
    Center for Geriatric Medicine and Network Aging Research, Heidelberg University, Heidelberg, Germany
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      While the complexity of sarcopenia pathogenesis has been universally accepted, gender-specific aspects have only received little attention. A recent study on microscopic characteristics of muscle composition in patients with hip fracture and sarcopenia showed a significant difference of fiber atrophy between men and women, with type II (“fast-twitch”) fiber atrophy being present only in men.
      • Tanganelli F.
      • Meinke P.
      • Hofmeister F.
      • et al.
      Type-2 muscle fiber atrophy is associated with sarcopenia in elderly men with hip fracture.
      This observation illustrates the need for a more gender-specific analysis of etiologic factors in sarcopenia, as this might also have therapeutic implications in the future.
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