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Letter to the Editor| Volume 22, ISSUE 8, P1774, August 2021

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Frailty and All-Cause Mortality in Older Adults: A Risk Assessment

      I read the recent article published in this journal written by Fan et al
      • Fan Y.
      • Huang J.
      • Zhou Y.
      • et al.
      Does the impact of frailty on all-cause mortality in older persons differ between women and men? A meta-analysis.
      with great interest. The authors conducted a meta-analysis on the association between frailty and all-cause mortality in older adults. The pooled risk ratios (RRs) of frail women and men for all-cause mortality were 2.41 [95% confidence interval (CI) 2.07-2.80] and 2.94 (95% CI 2.12-4.09), respectively. By using the frailty index, the pooled RRs (95% CIs) of frail women and men for all-cause mortality were 3.23 (2.16-4.83) and 2.63 (2.33-2.98), respectively. There were no significant sex differences in these associations, and I have 2 concerns about their study.
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      References

        • Fan Y.
        • Huang J.
        • Zhou Y.
        • et al.
        Does the impact of frailty on all-cause mortality in older persons differ between women and men? A meta-analysis.
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