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Letter to the Editor| Volume 22, ISSUE 9, P1883, September 2021

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Mortality Risk of Sarcopenia in Older Subjects

      I read the recent article published in this journal and written by Scheerman et al
      • Scheerman K.
      • Meskers C.G.M.
      • Verlaan S.
      • Maier A.B.
      Sarcopenia, low handgrip strength, and low absolute muscle mass predict long-term mortality in older hospitalized patients: An observational inception cohort study.
      with great interest. The authors investigated the association between sarcopenia, handgrip strength (HGS), muscle mass, and long-term mortality among hospitalized older patients aged ≥70 years. The hazard ratios (HRs) [95% confidence intervals (CIs)] of probable sarcopenia and sarcopenia for long-term mortality were 1.53 (1.08-2.18) and 1.71 (1.12-2.61), respectively. In male patients, HRs (95% CIs) of low HGS, skeletal muscle mass index, and appendicular lean mass for long-term mortality were 2.66 (1.40-5.05), 1.95 (1.06-3.58), and 1.99 (1.12-3.53), respectively. They concluded that sarcopenia could predict long-term mortality in older hospitalized patients, especially in men. The authors handled inpatient subjects, and the magnitude of effect size increased according to the progression of sarcopenia. Causes of stay in hospital might contribute to subsequent prognosis and also relate to the level of sarcopenia. I think that mortality risk among community-dwelling old subjects should also be checked to specify the relationship between sarcopenia and subsequent mortality.
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      References

        • Scheerman K.
        • Meskers C.G.M.
        • Verlaan S.
        • Maier A.B.
        Sarcopenia, low handgrip strength, and low absolute muscle mass predict long-term mortality in older hospitalized patients: An observational inception cohort study.
        J Am Med Dir Assoc. 2021; 22: 816-820.e2
        • Kitamura A.
        • Seino S.
        • Abe T.
        • et al.
        Sarcopenia: Prevalence, associated factors, and the risk of mortality and disability in Japanese older adults.
        J Cachexia Sarcopenia Muscle. 2021; 12: 30-38
        • Nakamura K.
        • Yoshida D.
        • Honda T.
        • et al.
        Prevalence and mortality of sarcopenia in a community-dwelling older Japanese population: the Hisayama Study.
        J Epidemiol. 2021; 31: 320-327