Abstract
Objectives
To analyze the effects of a program composed of resistance training and nutritional
interventions on functional capacity, maximal strength, and power output after 2 years
of follow-up, including 2 periods of 16 weeks of intervention followed by several
weeks of intervention cessation in frail patients with type 2 diabetes.
Design
MIDPOW is a substudy of a multicenter, multimodal intervention composed of resistance
training combined with a structured diabetes and nutritional education program in
frail and prefrail older people with type 2 diabetes (MID-Frail).
Setting and Participants
This study recruited 52 participants (mean age: 79 ± 5.6, 63% women), with type 2
diabetes mellitus, frail or prefrail using Fried's frailty phenotype.
Methods
Primary outcomes of this substudy were Short Physical Performance Battery (SPPB) and
maximal power output at 30% and 80% of 1RM.
Results
Each set of 16 weeks of intervention resulted in significant improvements in SPPB
performance by a mean of 36.1% at week 18 (P < .001) and 10.2% at week 68 (P < .05). Maximal power output improvements at 30% and 80% of the 1RM ranged from 45.2%
to 57.2% at week 18 (P < .01–.001); and no significant changes were observed after the second period of
intervention. After 2 years of follow-up, the SPPB and maximal power values observed
remained significantly higher than the baseline.
Conclusions and Implications
Resistance training combined with nutritional program improved SPPB, maximal strength,
and power output in older frail patients with diabetes. These improvements were maintained
above the basal levels after several weeks of intervention cessation during a 2-year
follow-up.
Keywords
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Article info
Publication history
Published online: July 12, 2021
Footnotes
The European Commission EU 7th Framework Program (Contract No 278803) funded the project.
The authors declare no conflicts of interest.
Identification
Copyright
© 2021 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
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