Setting and Participants
Conclusions and Implications
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Journal of the American Medical Directors Association
- Assessing the scope and appropriateness of prescribing cascades.J Am Geriatr Soc. 2019; 67: 1023-1026
- What is known about preventing, detecting, and reversing prescribing cascades: A scoping review.J Am Geriatr Soc. 2018; 66: 2079-2085
- Drug therapy.Lancet. 1995; 346: 32-36
- The prescribing cascade revisited.Lancet. 2017; 389: 1778-1780
- Hospitalization in older patients due to adverse drug reactions—the need for a prediction tool.Clin Interv Aging. 2016; 11: 497-505
- Adverse drug events as a cause of hospital admission in the elderly.Intern Med J. 2001; 31: 199-205
- American Geriatrics Society 2019 Updated AGS Beers Criteria(R) for potentially inappropriate medication use in older adults.J Am Geriatr Soc. 2019; 67: 674-694
- START (screening tool to alert doctors to the right treatment)--an evidence-based screening tool to detect prescribing omissions in elderly patients.Age Aging. 2007; 36: 632-638
- The dangers of ignoring the Beers criteria—the prescribing cascade.JAMA Intern Med. 2019; 179: 863-864
- Sequence symmetry analysis in pharmacovigilance and pharmacoepidemiologic studies.Eur J Epidemiol. 2017; 32: 567-582
- Taiwan's national health insurance research database: Past and future.Clin Epidemiol. 2019; 11: 349-358
- The validity of sequence symmetry analysis (SSA) for adverse drug reaction signal detection.Pharmacoepidemiol Drug Saf. 2013; 22: 496-502
- Prescription sequence symmetry analysis: Assessing risk, temporality, and consistency for adverse drug reactions across datasets in five countries.Pharmacoepidemiol Drug Saf. 2015; 24: 858-864
- Misdiagnosis and mistreatment of a common side-effect--angiotensin-converting enzyme inhibitor-induced cough.Br J Clin Pharmacol. 2010; 69: 200-203
- Angiotensin-converting enzyme inhibitor treatment and the development of urinary tract infections: A prescription sequence symmetry analysis.Drug Saf. 2013; 36: 1079-1086
- Association of statin use with storage lower urinary tract symptoms (LUTS): Data mining of prescription database.Int J Clin Pharmacol Ther. 2014; 52: 762-769
- Cholesterol-lowering drugs and antidepressants--a study of prescription symmetry.Pharmacoepidemiol Drug Saf. 1998; 7: 399-402
- Association of statin use with sleep disturbances: Data mining of a spontaneous reporting database and a prescription database.Drug Saf. 2014; 37: 421-431
- Association of atorvastatin with the risk of hepatotoxicity: A pilot prescription sequence symmetry analysis.Ther Clin Risk Manag. 2019; 15: 803-810
- Statins and nonsteroidal anti-inflammatory drugs-an analysis of prescription symmetry.Pharmacoepidemiol Drug Saf. 2006; 15: 510-511
- A sequence symmetry analysis of the interrelationships between statins, diabetes and skin infections.Br J Clin Pharmacol. 2019; 85: 2559-2567
- Association between statins and infections among patients with diabetes: A cohort and prescription sequence symmetry analysis.Pharmacoepidemiol Drug Saf. 2016; 25: 1124-1130
- Difference between the frequencies of antisecretory drug prescriptions in users of buffered vs. enteric-coated low-dose aspirin therapies.Int J Clin Pharmacol Ther. 2013; 51: 807-815
- Magnitude of and characteristics associated with the treatment of calcium channel blocker-induced lower-extremity edema with loop diuretics.JAMA Netw Open. 2019; 2: e1918425
- An evaluation of a potential calcium channel blocker-lower-extremity edema-loop diuretic prescribing cascade.J Am Pharm Assoc. 2018; 58: 534-539.e534
- NHI-PharmaCloud in Taiwan--A preliminary evaluation using the RE-AIM framework and lessons learned.Int J Med Inform. 2015; 84: 817-825
- Physicians' adherence to guidelines for empirical treatment of urinary tract infection in Taiwan.J Microbiol Immunol Infect. 2007; 40: 532-536
Y.C. and S.-T.H. contributed equally.
S.-T.H., F.Y.H., and L.K.C. received research assistantships from research projects (MOST 109–2634-F-010–001, MOST 110–2634-F-010–001) sponsored by the Ministry of Science and Technology Taiwan.
The authors declare no conflicts of interest.
Author Contributions: All authors meet the criteria for authorship stated in the Uniform Requirements for Manuscripts Submitted to Biomedical Journals. All authors drafted the article, revised it critically for important intellectual content, and approved the final version to be published. S.-T.H., T.C.H., F.Y.H., and L.K.C. designed the research. Y.C., S.-T.H., F.Y.H., and L.K.C. wrote the paper. Y.C. and T.C.H. performed the literature search. S.-T.H. analyzed data. F.Y.H. and L.K.C. provided critical methodological inputs. S.-T.H. and F.Y.H. provided methodological and statistical inputs. L.N.P. and L.K.C. contributed to the clinical interpretation. F.Y.H. and L.K.C. are guarantors.
The identification numbers for all entries in the NHIRD were encrypted to protect the privacy of individual patients. The study protocol was approved by the Institutional Review Board of the National Taiwan University Hospital (No. 201803134RINC).