Overtreatment by glucose-lowering treatment (GLT) is frequent, and may induce harmful
hypoglycemic events in older people with type 2 diabetes (T2D), significantly increasing
morbidity and mortality.
1
Avoiding overtreatment by GLT, either by prescribing appropriate GLT according to
their individual risks-benefits balance or by deprescribing GLT, is therefore a key
issue in the management of older patients, as recommended by various scientific societies
these last years.
2
Nevertheless, there is currently no consensus on the definition of GLT overtreatment
in older people,
3
which prevents a clear statement on which patients should undergo deprescribing of
GLT. It is therefore worthwhile to define the profiles of patients for whom GLT should
be deprescribed. This systematic review of clinical practice guidelines (CPGs) aimed
to compare the recommendations defining profiles of older patients in whom deprescribing
GLT is recommended.To read this article in full you will need to make a payment
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References
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- Diabetes in older people.Can J Diabetes. 2018; 42: S283-S295
- Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline.Can Fam Physician. 2017; 63: 832-843
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Article info
Publication history
Published online: January 23, 2023
Publication stage
In Press Uncorrected ProofFootnotes
This study was supported by a postdoctoral grant (Bourse d’Excellence WBI.world) awarded to Antoine Christiaens from Wallonie-Bruxelles International, Belgium (ref. SUB/2021/515794). The funding body played no part in the design of the study; collection, analysis, and interpretation of data; or in writing the manuscript.
The authors declare no conflicts of interest.
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© 2022 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
